170033-55-3 Usage
Description
(R)-3-Methyl-1-(phenylmethyl)piperazin-2-one, a piperazinone derivative with the molecular formula C13H18N2O, belongs to the class of organic compounds known as N-alkylpiperazines. This chemical compound is frequently utilized in the fields of medicinal chemistry and pharmacology due to its capacity to modulate various neurotransmitter systems within the central nervous system. Its potential applications extend to the treatment of a range of neurological and psychiatric disorders, and it is also considered as a building block for the synthesis of other pharmaceuticals and organic compounds.
Uses
Used in Pharmaceutical Synthesis:
(R)-3-Methyl-1-(phenylmethyl)piperazin-2-one is used as a building block for the synthesis of other pharmaceuticals and organic compounds, leveraging its structural properties to create a diverse array of molecules with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (R)-3-Methyl-1-(phenylmethyl)piperazin-2-one is used as a modulator of neurotransmitter systems in the central nervous system, which can be crucial for the development of treatments targeting neurological and psychiatric disorders.
Used in Neurology and Psychiatry:
(R)-3-Methyl-1-(phenylmethyl)piperazin-2-one is employed as a potential therapeutic agent for the treatment of various neurological and psychiatric disorders, due to its ability to interact with and modulate neurotransmitter systems in the brain.
Used in Drug Development:
(R)-3-Methyl-1-(phenylmethyl)piperazin-2-one is utilized in drug development as a starting point for the creation of novel compounds with specific therapeutic targets, potentially leading to the discovery of new medications for a variety of conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 170033-55-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,0,3 and 3 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 170033-55:
(8*1)+(7*7)+(6*0)+(5*0)+(4*3)+(3*3)+(2*5)+(1*5)=93
93 % 10 = 3
So 170033-55-3 is a valid CAS Registry Number.
170033-55-3Relevant articles and documents
Asymmetric Synthesis of 2,6-Methylated Piperazines
Mickelson, John W.,Belonga, Kenneth L.,Jacobsen, Jon E.
, p. 4177 - 4183 (2007/10/02)
The complete series of enantiopure 2,6-methylated piperazines was synthesized utilizing two alternative reactions in the key bond-forming step.The dimethyl enantiomers, (2R,6R)- and (2S,6S)-2,6-dimethylpiperazine (1, 2), were prepared using either a diastereoselective triflate alkylation or a novel intermolecular Mitsunobu reaction to set the required stereochemistry.The monomethyl derivatives, (R)- and (S)-tert-butyl 2-methyl-1-piperazinecarboxylate (3, 4) were also synthesized employing the Mitsunobu cyclization strategy while the trimethyl compounds, (R)- and (S)-2,2,6- trimethylpiperazine (5, 6) were prepared using an enantiospecific triflate alkylation as the principal reaction.These methods represent efficient, general strategies for preparing a variety of 2,6-methylated piperazines for which the absolute stereochemistry can be readily controlled.
