170210-43-2 Usage
Description
(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl methanesulfonate is a specific stereoisomer of a compound that contains a dioxolane ring with a substituted imidazole group. It also features a methanesulfonate moiety, which is commonly used as a leaving group in organic synthesis. (2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl methanesulfonate may have potential applications in medicinal chemistry as a pharmaceutical intermediate or as a building block for the synthesis of other molecules with biological activity. Its stereochemistry and specific substituents are crucial in determining its properties and potential uses.
Uses
Used in Pharmaceutical Industry:
(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl methanesulfonate is used as a pharmaceutical intermediate for the development of new drugs. Its unique structure and stereochemistry allow it to be a valuable component in the synthesis of complex molecules with potential therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl methanesulfonate serves as a building block for the synthesis of other molecules with biological activity. Its specific substituents and dioxolane ring system can be utilized to create novel compounds with potential use in treating various diseases and conditions.
Used in Organic Synthesis:
(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl methanesulfonate is used as a leaving group in organic synthesis. Its methanesulfonate moiety can be easily displaced in chemical reactions, making it a useful component in the synthesis of a wide range of organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 170210-43-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,2,1 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 170210-43:
(8*1)+(7*7)+(6*0)+(5*2)+(4*1)+(3*0)+(2*4)+(1*3)=82
82 % 10 = 2
So 170210-43-2 is a valid CAS Registry Number.
170210-43-2Relevant articles and documents
Stereoselective Syntheses of Both Enantiomers of Ketoconazole from (R)- and (S)-Epichlorohydrin
Camps, Pelayo,Farres, Xavier,Garcia, Luisa,Ginesta, Joan,Pascual, Jaume,et al.
, p. 1283 - 1294 (2007/10/03)
Stereoselective syntheses of both enantiomers of ketoconazole (1) from commercially available (R)- or (S)-epichlorohydrin has been developed.The key-step of syntheses involves the selective substitution of the methylene chlorine atom by benzoate on a mixture of (2S,4R)-14a and (2R,4R)-15a or of their enentiomers, followed by crystalization of the corresponding cis-benzoates, (2R,4R)-18 or (2S,4S)-18, from which (+)- or (-)-1 were obtained as described for (+/-)-1.The ee's of (+)- and (-)-ketocanazole were determined by HPLC on the CSP Chiracel OD-H.
