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170291-52-8

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170291-52-8 Usage

| Molecular weight

| 389.47 g/mol |

| Chemical structure

| 1-Piperidinecarboxylic acid, 4-(4-fluorophenyl)-4-(hydroxymethyl)-, 1,1-dimethylethyl ester |

| Synonyms

| Tadalafil |

| Medicinal use

| Treatment of erectile dysfunction and benign prostatic hyperplasia |

| Mechanism of action

| Phosphodiesterase 5 (PDE5) inhibitor, relaxes muscles, and increases blood flow to certain areas of the body |

| Administration

| Taken as needed, about 30 minutes before sexual activity |

| Duration

| Can last in the system for up to 36 hours |

| Side effects

| May include headache, stomach upset, muscle pain, and back pain |

| Precautions

| Consult with a healthcare professional before use to ensure it is safe and appropriate |

Check Digit Verification of cas no

The CAS Registry Mumber 170291-52-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,2,9 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 170291-52:
(8*1)+(7*7)+(6*0)+(5*2)+(4*9)+(3*1)+(2*5)+(1*2)=118
118 % 10 = 8
So 170291-52-8 is a valid CAS Registry Number.

170291-52-8Downstream Products

170291-52-8Relevant articles and documents

Development of a scalable route to a dual NK-1/serotonin receptor antagonist

Risatti, Christina,Natalie, Kenneth J.,Shi, Zhongping,Conlon, David A.

, p. 257 - 264 (2013/04/10)

The evolution of a process for the preparation of a new heterocyclic dual NK1/serotonin receptor antagonist is described. The final synthesis features a telescoped sequence in which an iron(III)-catalyzed Grignard coupling is followed by a benzylic chlori

SUBSTITUTED HETEROCYCLIC ETHERS AND THEIR USE IN CNS DISORDERS

-

Page/Page column 36, (2009/09/05)

The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.

NK-1 AND SEROTONIN TRANSPORTER INHIBITORS

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Page/Page column 75, (2010/11/28)

The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both.

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