1705-85-7

Basic information

• Product Name: 6-METHYLCHRYSENE
• Synonyms: 6-methyl-chrysen;6-METHYLCHRYSENE;67405 6-METHYLCHRYSENE (PURITY);CHRYSENE,6-METHYL-
• CAS NO: 1705-85-7
• Molecular Formula: C₁₉H₁₄
• Molecular Weight: 242.31
• EINECS: 216-942-2
• Mol File: 1705-85-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 161.5°C
• Boiling Point: 465.14°C (rough estimate)
• Flash Point: 217.8°C
• Appearance: /
• Density: 1.1011 (estimate)
• Vapor Pressure: 7.61E-08mmHg at 25°C
• Refractive Index: 1.7480 (estimate)
• Storage Temp.: 2-8°C
• Water Solubility: 65ug/L(27 oC)
• CAS DataBase Reference: 6-METHYLCHRYSENE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHYLCHRYSENE(1705-85-7)
• EPA Substance Registry System: 6-METHYLCHRYSENE(1705-85-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-50
• Safety Statements: 61
• Hazardous Substances Data: 1705-85-7(Hazardous Substances Data)

Usage

Description

6-Methylchrysene, also known as 6-MeChry, is a methylated chrysene compound that belongs to the group of polycyclic aromatic hydrocarbons (PAHs). It is an aryl hydrocarbon receptor (AhR) agonist and is found as a constituent in cigarette smoke. Due to its chemical structure and properties, 6-Methylchrysene has been classified as possibly carcinogenic to humans.

Uses

Used in Research Applications:
6-Methylchrysene is used as a research compound for studying the effects of AhR agonists on biological systems. It helps scientists understand the molecular mechanisms underlying the activation of the aryl hydrocarbon receptor and its role in various cellular processes.
Used in Environmental and Occupational Health Assessments:
6-Methylchrysene is utilized as a biomarker for assessing exposure to cigarette smoke and other sources of PAHs in environmental and occupational settings. Monitoring the levels of 6-Methylchrysene can provide valuable information on the potential health risks associated with exposure to these harmful compounds.
Used in Toxicological Studies:
6-Methylchrysene serves as a model compound in toxicological research to investigate the carcinogenic potential of PAHs. These studies contribute to the development of guidelines and regulations aimed at reducing human exposure to carcinogenic substances.

InChI:InChI=1/C19H14/c1-13-12-19-16-8-3-2-6-14(16)10-11-18(19)17-9-5-4-7-15(13)17/h2-12H,1H3

Upstream product

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• 61161-21-5 2-(1'-methylethenyl)-1-iodobenzene 
• 269066-75-3 2-bromo-1-naphthaldehyde 
• 7647-01-0 hydrogenchloride 
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• 7446-70-0 aluminium trichloride 
• 100064-41-3 5,11-dimethyl-7,8,9,10,10a,10b,11,12-octahydro-6aH-chrysen-6-one 
• 81465-03-4 12-Methyl-1,2,4a,12a-tetrahydro-chrysene 
• 31136-25-1 (E)-1-methyl-4-styrylnaphthalene 
• 917-64-6 methyl magnesium iodide 
• 71-43-2 benzene 
• 110051-41-7 1-(2-Phenyl-propyl)-1,2,3,4-tetrahydro-[2]naphthol 
• 113012-61-6 4b,12-dimethyl-4b,5,6,10b,11,12-hexahydro-chrysene 

Downstream Products

• 33895-44-2 6-Chrysemylmethyl-triphenylphosphonium-bromid 
• 74976-53-7 6-((E)-2-p-Tolyl-vinyl)-chrysene 

Relevant articles and documents

Palladium-Catalyzed Sequential Vinyl C–H Activation/Dual Decarboxylation: Regioselective Synthesis of Phenanthrenes and Cyclohepta[1,2,3-de]naphthalenes

The application of a C(vinyl), C(aryl)-palladacycle from vinyl-containing substrates is challenging due to the interference of a reactive double bond in palladium catalysis. This Letter describes a [4 + 2] or [4 + 3] cyclization based on a C(vinyl), C(aryl)-palladacycle by employing α-oxocarboxylic acids as the insertion units under a palladium/air system. The reaction proceeded through the key vinyl C–H activation and dual decarboxylation sequence, forming phenanthrenes and cyclohepta[1,2,3-de]naphthalenes regioselectively in good yields. The synthetic versatility of this protocol is highlighted by the gram-scale synthesis and synthesizing functional material molecule.

Characterization of the combustion products of polyethylene

Polyethylene (PE) was burned in a tube-type furnace with an air flow at a temperature of 600~900°C. Combustion products were collected with glass wool, glass fiber filter, and XAD-2 adsorbent. The analysis of the products was performed with GC-FID and GC-MSD. At low temperature, hydrocarbons were the major components, while at higher temperature the products were composed of polycyclic aromatic hydrocarbons. With the high performance of the Hewlett-Packard 6890GC-5973MSD, more compounds were identified in comparison with previous studies.

Acid-catalyzed rearrangement of cyclobutanols. Syntheses of chrysenes, cyclopentenophenanthrenes, and diarylmethanes

Acid-catalyzed reactions of 8-aryl or 8,8-diarylbicyclooct-2-en-7-ols lead to tetrahydrophenanthrene derivatives.For example 8-(1-naphthyl)-bicyclooct-2-en-7-ols give substituted chrysenes in methanesulphonic acid.In the case of the homologous 7-aryl or 7,7-diarylbicyclohept-2-en-6-ols a novel transformation of diarylmethanes is observed.A mechanism is proposed which accounts for the product distribution observed in these rearrangements.