171194-77-7Relevant articles and documents
Biocatalytic racemization of synthetically important functionalized α-hydroxyketones using microbial cells
Nestl, Bettina M.,Bodlenner, Anne,Stuermer, Rainer,Hauer, Bernhard,Kroutil, Wolfgang,Faber, Kurt
, p. 1465 - 1474 (2007)
Biocatalytic racemization of straight-chain and cyclic acyloins bearing (halo)alkyl, alkenyl and functionalized (hetero)aryl moieties was accomplished using whole resting cells of bacteria, fungi and yeasts. Mild physiological reaction conditions ensured the suppression of undesired side-reactions, such as elimination or condensation. This biocatalytic protocol represents a useful tool for the clean racemization of unwanted enantiomers of synthetically important α-hydroxyketones derived from kinetic resolution.
The enantiomers of Iralia: preparation and odour evaluation
Abate, Agnese,Brenna, Elisabetta,Fuganti, Claudio,Malpezzi, Luciana,Serra, Stefano
, p. 1145 - 1153 (2008/02/10)
The enantiomers of methyl ionones 1 and 2 were prepared by an enzyme-catalysed approach. Their odour properties were evaluated by skilful perfumers.
On 1,4-Diastereoselectivity in the Aldol Condensation of Methyl Ketones
Trost, Barry M.,Urabe, Hirokazu
, p. 3982 - 3983 (2007/10/02)
2-(Trimethylsiloxy)-3-RO-1-butene serves as practical and simple chiral enolate equivalent of a methyl ketone for asymmetric aldol condensations.
