17122-78-0 Usage
Description
4-[(2E)-2-(Hydroxyimino)ethanoyl]aminobenzoic acid is a chemical compound with the molecular formula C11H10N2O4, belonging to the benzoic acid derivatives. It features a substituted amino group and a hydroxyimino group, which contribute to its unique structure and properties. 4-[(2E)-2-(HYDROXYIMINO)ETHANOYL]AMINOBENZOIC ACID holds promise in pharmaceuticals and medical research due to its potential applications and biological activities, although further research is required to fully explore its capabilities.
Uses
Used in Pharmaceutical Industry:
4-[(2E)-2-(Hydroxyimino)ethanoyl]aminobenzoic acid is used as a building block for the synthesis of various pharmaceutical compounds, leveraging its unique structure to create new medications with potential therapeutic benefits.
Used in Medical Research:
In the field of medical research, 4-[(2E)-2-(Hydroxyimino)ethanoyl]aminobenzoic acid may be utilized to investigate its potential biological activities, which could lead to the discovery of new treatments or diagnostic tools for various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 17122-78-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,2 and 2 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17122-78:
(7*1)+(6*7)+(5*1)+(4*2)+(3*2)+(2*7)+(1*8)=90
90 % 10 = 0
So 17122-78-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2O4/c12-8(5-10-15)11-7-3-1-6(2-4-7)9(13)14/h1-5,15H,(H,11,12)(H,13,14)/b10-5+
17122-78-0Relevant articles and documents
Synthesis, anti-lung cancer activity and molecular docking study of 3-methylene-2-oxoindoline-5-carboxamide derivatives
Ai, Juntao,Lv, Meng,Li, Xiaohui,Chen, Zhuo,Hu, Gaoyun,Li, Qianbin
, p. 161 - 170 (2018/04/17)
A series of 3-methylene-2-oxoindoline-5-carboxamide derivatives were synthesized in appreciable yield by using 4-aminobenzoic acid as a starting material. The preliminary biological test results showed that most compounds displayed potent inhibitory activity against proliferation of human lung adenocarcinoma epithelial cell line (A549) in MTT assay. Compound 6l displayed the highest potency (IC50 = 3.0 μM). The western blot analysis demonstrated a correlation between anti-proliferative activity of active compounds and blockade of the phosphorylation of extracellular signal-regulated kinases (ERK1/2). The docking study also provides new insights into further optimization of 3-methylene-2-oxoindoline-5-carboxamide derivatives for the discovery of more potent RAF/MEK/ERK pathway regulators as anti-lung cancer agents.