171721-03-2Relevant articles and documents
A green synthetic clevudine pharmaceutical intermediates
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, (2019/03/29)
The invention relates to a green synthetic clevudine pharmaceutical intermediates method, comprises the following steps: The formula II compound is dissolved in the organic solvent, under ice bath by adding 40% of the hydrobromic, tetrabutyl ammonium fluo
IMPROVED PROCESS FOR THE PREPARATION OF CLEVUDINE AS ANTI-HBV AGENT
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Page/Page column 13-14, (2008/12/06)
Disclosed herein is an improved method for preparing l -(2'-deoxy-2'- fluoro-beta-L-arabinofuranosyl) thymine (clevudine) useful as an anti-HBV (hepatitis B vims) agent. The method comprises an improved purification process of 2-O-imidazolylsulfonyl-l,3,5
New synthesis of L-FMAU from L-arabinose
Sznaidman, Marcos L.,Almond, Merrick R.,Pesyan, Amir
, p. 155 - 163 (2007/10/03)
A new synthesis of 2′-deoxy-2′-fluoro-5-methyl-β-L-arabinofuranosyl uracil (13, L-FMAU) was achieved in 10 steps from L-arabinose.