171721-34-9 Usage
Description
(S)-2-((3-NITROPHENOXY)METHYL)OXIRANE is a chiral epoxide chemical compound with a molecular formula of C9H9NO4. It features a nitrophenyl group and an epoxide functional group, making it a significant intermediate in the synthesis of various organic compounds. Its chiral nature is essential in the pharmaceutical industry for producing enantiomerically pure compounds, which ensures the safety and efficacy of drugs.
Uses
Used in Pharmaceutical Industry:
(S)-2-((3-NITROPHENOXY)METHYL)OXIRANE is used as a building block for the production of pharmaceuticals. Its chiral nature allows for the creation of enantiomerically pure compounds, which is crucial for the safety and efficacy of drugs.
Used in Agrochemical Industry:
In the agrochemical industry, (S)-2-((3-NITROPHENOXY)METHYL)OXIRANE is used as an intermediate in the synthesis of various agrochemicals, contributing to the development of effective and targeted products for agricultural applications.
Used in Fine Chemicals Production:
(S)-2-((3-NITROPHENOXY)METHYL)OXIRANE is also utilized as a valuable intermediate in the synthesis of a wide range of fine chemicals, showcasing its versatility and importance in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 171721-34-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,1,7,2 and 1 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 171721-34:
(8*1)+(7*7)+(6*1)+(5*7)+(4*2)+(3*1)+(2*3)+(1*4)=119
119 % 10 = 9
So 171721-34-9 is a valid CAS Registry Number.
171721-34-9Relevant articles and documents
An unusual (R)-selective epoxide hydrolase with high activity for facile preparation of enantiopure glycidyl ethers
Zhao, Jing,Chu, Yan-Yan,Li, Ai-Tao,Ju, Xin,Kong, Xu-Dong,Pan, Jiang,Tang, Yun,Xu, Jian-He
, p. 1510 - 1518 (2011/08/03)
A novel epoxide hydrolase (BMEH) with unusual (R)-enantioselectivity and very high activity was cloned from Bacillus megaterium ECU1001. Highest enantioselectivities (E>200) were achieved in the bioresolution of ortho-substituted phenyl glycidyl ethers and para-nitrostyrene oxide. Worthy of note is that the substrate structure remarkably affected the enantioselectivities of the enzyme, as a reversed (S)-enantiopreference was unexpectedly observed for the ortho-nitrophenyl glycidyl ether. As a proof-of-concept, five enantiopure epoxides (>99% ee) were obtained in high yields, and a gram-scale preparation of (S)-ortho-methylphenyl glycidyl ether was then successfully performed within a few hours, indicating that BMEH is an attractive biocatalyst for the efficient preparation of optically active epoxides. Copyright
