171869-95-7

Basic information

• Product Name: Palmatine chloride hydrate
• Synonyms: BUFFER SP2;KIT DNA/RNA EZ-96 1X96 TESTS;PALMATINE CHLORIDE HYDRATE;PALMATINECHLORIDE95%;PalMatine chloride hydrate 97%;Hydrochloric PalMatine
• CAS NO: 171869-95-7
• Molecular Formula: C21H24ClNO5
• Molecular Weight: 405.87
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Isoquinolines;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 171869-95-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 206-207 °C (dec.)(lit.)
• Flash Point: >230 °F
• Appearance: /
• CAS DataBase Reference: Palmatine chloride hydrate(CAS DataBase Reference)
• NIST Chemistry Reference: Palmatine chloride hydrate(171869-95-7)
• EPA Substance Registry System: Palmatine chloride hydrate(171869-95-7)

Safety Data

• Hazard Codes: Xn
• Statements: 20/22-36/38
• Safety Statements: 24-45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 171869-95-7(Hazardous Substances Data)

Usage

Description

Palmatine chloride hydrate, commonly known as Palmatine, is an alkaloid derived from various plant sources, including goldenseal (Hydrastis canadensis L.) root powder. It is recognized as a potential phototoxin and exhibits low quantum yields for fluorescence. The compound has been studied for its Raman spectra and DFT calculations, providing insights into its molecular structure and properties.

Uses

Used in Pharmaceutical Industry:
Palmatine chloride hydrate is used as an alkaloid standard in the method validation for the determination of berberine, hydrastine, and canadine in goldenseal (Hydrastis canadensis L.) root powder. This application is crucial for ensuring the quality and efficacy of herbal medicines containing these alkaloids.
Used in Chemical Research:
In the field of chemical research, Palmatine chloride hydrate is utilized in the preparation of 8-heteroaryl-7,8-dihydroprotoberberine. Palmatine chloride hydrate is of interest due to its potential applications in various chemical and pharmaceutical processes.
Used in Spectroscopy:
Palmatine chloride hydrate is employed in the study of FT-Raman and surface-enhanced Raman scattering (SERS) spectra of three related alkaloid dyes, namely palmatine, jatrorrhizine, and coptisine. This application aids in understanding the molecular interactions and properties of these alkaloids, which can be valuable for their use in various industries, including pharmaceuticals and materials science.

InChI:InChI=1/C21H22NO4.ClH.H2O/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;;/h5-6,9-12H,7-8H2,1-4H3;1H;1H2/q+1;;/p-1