171898-36-5

Basic information

• Product Name: methyl (S)-N-benzoyl-3-(1,4-cyclohexadien-1-yl)alaninate
• Synonyms: methyl (S)-N-benzoyl-3-(1,4-cyclohexadien-1-yl)alaninate
• CAS NO: 171898-36-5
• Molecular Weight: 285.343
• Mol File: 171898-36-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (S)-N-benzoyl-3-(1,4-cyclohexadien-1-yl)alaninate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (S)-N-benzoyl-3-(1,4-cyclohexadien-1-yl)alaninate(171898-36-5)
• EPA Substance Registry System: methyl (S)-N-benzoyl-3-(1,4-cyclohexadien-1-yl)alaninate(171898-36-5)

Safety Data

• Hazardous Substances Data: 171898-36-5(Hazardous Substances Data)

Upstream product

• 16055-12-2 (L)-(-)-2,5-dihydro-phenylalanine 
• 67-56-1 methanol 
• 171898-35-4 N-benzoyl(cyclohexa-1,4-dienyl)-L-alanine 

Downstream Products

• 189952-35-0 (S)-2-Benzoylamino-3-(2-oxo-3-phenyl-2H-isoxazolo[2,3-a]pyrimidin-5-yl)-propionic acid methyl ester 
• 189952-41-8 (S)-2-Benzoylamino-3-(2-benzoyl-pyrimidin-4-yl)-propionic acid methyl ester 
• 189952-36-1 (S)-2-Benzoylamino-3-(2-benzyl-pyrimidin-4-yl)-propionic acid methyl ester 
• 86555-45-5 (2S)-N-benzoyl-L-aspartic acid dimethyl ester 
• 1026041-22-4 (S)-2-Benzoylamino-4,6-dioxo-hexanoic acid methyl ester 

Relevant articles and documents

Ozonolysis of (cyclohexa-1,4-dienyl)-L-alanine. An approach to the synthesis of new unnatural aminoacids. X-Ray molecular structure of 2-hydroxy-7-methyl-3-phenylpyrazolopyrimidine

The aromatic ring in L-phenylalanine was transformed into isoxazolyl, N-phenylpyrazolyl, and the bicyclic pyrazolopyrimidinyl groups, by a combination of Birch reduction and ozonolysis, followed by condensation with the relevant binucleophiles.The ozonolysis was carried out on the N-acylated esters of cyclohexa-1,4-dienylalanine.The resulting N-acylated esters of heterocyclic alanine derivatives were obtained without isolation of the ozonolysis products. 4-Phenylpyrazolidine-3,5-dione was used as a 'hydrazine donor' in the construction of pyrazolyl group, as direct condensation with hydrazine was successful.