17197-20-5 Usage
Description
(Z)-3-amino-3-(4-chlorophenyl)acrylonitrile, with the molecular formula C10H8ClN3, is a chemical compound that belongs to the class of nitriles. It features an amino group and a phenyl group, which contribute to its unique chemical properties and potential applications. This versatile compound has garnered interest in the fields of organic synthesis and pharmaceutical research due to its ability to serve as a building block for the creation of biologically active compounds and as a precursor for the synthesis of functionalized organic molecules.
Uses
Used in Organic Synthesis:
(Z)-3-amino-3-(4-chlorophenyl)acrylonitrile is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for further chemical reactions and modifications, making it a valuable component in the development of new molecules with specific properties and applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (Z)-3-amino-3-(4-chlorophenyl)acrylonitrile is used as a starting material for the development of new drugs. Its potential pharmacological activities have been investigated, and it has shown promise in the creation of biologically active compounds that could be used for therapeutic purposes.
Used in the Preparation of Functionalized Organic Molecules:
(Z)-3-amino-3-(4-chlorophenyl)acrylonitrile is also utilized as a precursor for the preparation of functionalized organic molecules. These molecules can have a wide range of applications, from being used as components in materials science to serving as active ingredients in the pharmaceutical and agrochemical industries.
Overall, (Z)-3-amino-3-(4-chlorophenyl)acrylonitrile is a chemical compound with significant potential in various scientific and industrial applications, particularly in the fields of organic synthesis and pharmaceutical research. Its unique structure and properties make it a valuable asset in the development of new and innovative products.
Check Digit Verification of cas no
The CAS Registry Mumber 17197-20-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,9 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17197-20:
(7*1)+(6*7)+(5*1)+(4*9)+(3*7)+(2*2)+(1*0)=115
115 % 10 = 5
So 17197-20-5 is a valid CAS Registry Number.
17197-20-5Relevant articles and documents
Silver-promoted regio- and stereoselective aminocyanation of alkynes for the synthesis of β-aminoacrylonitriles using N-isocyanoiminotriphenylphosphorane
Chen, Lingnan,Cao, Shanshan,Zhang, Jingping,Wang, Zikun
supporting information, p. 1678 - 1681 (2019/05/29)
The silver-promoted intermolecular aminocyanation of alkynes for the synthesis of (Z)-β-aminoacrylonitriles is reported, using N-isocyanoiminotriphenylphosphorane (NIITP) as both the nitrile and amine source. The transformation proceeds in moderate to good yields, and in a regio- and stereoselective manner, using a wide range of acetylenes.
Enantioselective biocatalytic hydrolysis of β-aminonitriles to β-amino-amides using Rhodococcus rhodochrous ATCC BAA-870
Chhiba, Varsha,Bode, Moira L.,Mathiba, Kgama,Kwezi, Wendy,Brady, Dean
experimental part, p. 68 - 74 (2012/04/10)
A range of β-aminonitriles (3-amino-3-phenylpropanenitrile and derivatives) were synthesised by reaction of various benzonitriles with acetonitrile and subsequent reduction of the resulting acrylonitrile products. These compounds were hydrolysed to the co
Rhodium-catalyzed asymmetric hydrogenation of β-acetylamino acrylonitriles
Ma, Miaofeng,Hou, Guohua,Wang, Junru,Zhang, Xumu
experimental part, p. 506 - 511 (2011/06/17)
The rhodium-catalyzed asymmetric hydrogenation of β-acetylamino acrylonitriles was investigated by using monophosphine and bisphosphine ligands. It was found that an Rh-QuinoxP complex exhibited high enantioselectivities for β-aryl substituted β-acetylamino acrylonitriles and the Rh-JosiPhos CyPF-t-Bu complex was proven to be effective for the hydrogenation of tetrasubstituted olefins from cyclic β-acetylamino acrylonitriles.
