1722-62-9 Usage
Description
Mepivacaine hydrochloride is a local anesthetic that is chemically and pharmacologically related to the amide-type local anesthetics. It is a white solid and is commonly used in medical procedures to provide pain relief during surgeries and other medical interventions. Mepivacaine hydrochloride is also used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
Uses
Used in Pharmaceutical Industry:
Mepivacaine hydrochloride is used as a local anesthetic for various medical procedures, including local infiltration and peripheral nerve block. It is effective in providing pain relief and is often administered via injection.
Used in Quality Control:
Mepivacaine hydrochloride serves as a pharmaceutical secondary standard for application in quality control. It provides pharmaceutical laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Used in Anesthetic Applications:
Mepivacaine hydrochloride is used as a local anesthetic in medical procedures, such as surgeries and dental treatments, to numb the affected area and reduce pain.
Used in Anti-inflammatory and Analgesic Applications:
Mepivacaine hydrochloride is also used as an anti-inflammatory and analgesic, helping to reduce inflammation and alleviate pain in various medical conditions.
Used in Chromatography:
Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography, ensuring the accuracy and reliability of the results.
Brand Names:
Some of the brand names for Mepivacaine hydrochloride include Arestocaine Hydrochloride (Solvay Pharmaceuticals), Carbocaine (Hospira), Isocaine Hydrochloride (Novocol), Polocaine (AstraZeneca), Polocaine (Dentsply), and Scandonest (Deproco).
Biological Functions
Mepivacaine hydrochloride (Carbocaine) is longer
acting than lidocaine and has a more rapid onset of action
(3–5 minutes). Topical application is not effective.
It has been widely used in obstetrics, but its use has declined
recently because of the early transient neurobehavioral
effects it produces. Adverse reactions associated
with mepivacaine are generally similar to those
produced by other local anesthetics. It can be used with
epinephrine or levonordefrin (dental use only).
Biochem/physiol Actions
Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.
Safety Profile
skin irritant. Questionable carcinogen with
Check Digit Verification of cas no
The CAS Registry Mumber 1722-62-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,2 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1722-62:
(6*1)+(5*7)+(4*2)+(3*2)+(2*6)+(1*2)=69
69 % 10 = 9
So 1722-62-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H