172276-07-2

Basic information

• Product Name: Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((1R,2R)-2-hydroxy-cyclohexyloxy)-tetrahydro-pyran-3-yl ester
• Synonyms: Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((1R,2R)-2-hydroxy-cyclohexyloxy)-tetrahydro-pyran-3-yl ester
• CAS NO: 172276-07-2
• Molecular Weight: 446.452
• Mol File: 172276-07-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((1R,2R)-2-hydroxy-cyclohexyloxy)-tetrahydro-pyran-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((1R,2R)-2-hydroxy-cyclohexyloxy)-tetrahydro-pyran-3-yl ester(172276-07-2)
• EPA Substance Registry System: Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((1R,2R)-2-hydroxy-cyclohexyloxy)-tetrahydro-pyran-3-yl ester(172276-07-2)

Safety Data

• Hazardous Substances Data: 172276-07-2(Hazardous Substances Data)

Upstream product

• 1072-86-2 (1R,2R)-trans-1,2-cyclohexanediol 
• 74808-10-9 2,3,4,6-tetra-O-acetyl-D-galactopyranosyl trichloroacetimidate 

Downstream Products

• 188636-79-5 2-(2-{(2S,4aR,6R,7R,8S,8aS)-8-Benzyloxy-2-phenyl-6-[(1R,2R)-2-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-cyclohexyloxy]-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yloxy}-ethyl)-malonic acid dimethyl ester 
• 188636-73-9 (2S,4aR,6R,7R,8S,8aS)-7-(2-Allyloxy-ethoxy)-8-benzyloxy-2-phenyl-6-[(1R,2R)-2-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-cyclohexyloxy]-hexahydro-pyrano[3,2-d][1,3]dioxine 
• 172147-74-9 Acetic acid (2R,3S,4S,5R,6R)-3,5-diacetoxy-2-acetoxymethyl-6-[(1R,2R)-2-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-cyclohexyloxy]-tetrahydro-pyran-4-yl ester 

Relevant articles and documents

Pitfalls in the synthesis and biological evaluation of sialyl-Lewis(x) mimetics as potential selectin antagonists

The lower molecular weight analog 12 of sialyl Lewis(x) was prepared and effected equal binding affinity to E- and P-selectin compared to the parent tetrasaccharide. If 12 was prepared using acidic ion exchange resins, false positive test were produced, especially binding to P-selectin seemed to be considerably enhanced. Traces of polyanions released from the resins which are difficult to detect by routine analysis were identified to be highly potent selectin inhibitors, probably by their action on a non-carbohydrate binding site.