1723-29-1

Basic information

• Product Name: Acetic acid, [(2-formyl-3-thienyl)thio]-, methyl ester
• CAS NO: 1723-29-1
• Molecular Formula: C8H8O3S2
• Molecular Weight: 216.282
• Mol File: 1723-29-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid, [(2-formyl-3-thienyl)thio]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [(2-formyl-3-thienyl)thio]-, methyl ester(1723-29-1)
• EPA Substance Registry System: Acetic acid, [(2-formyl-3-thienyl)thio]-, methyl ester(1723-29-1)

Safety Data

• Hazardous Substances Data: 1723-29-1(Hazardous Substances Data)

Upstream product

• 930-96-1 3-bromo-2-thiophenecarboxaldehyde 

Downstream Products

• 31486-86-9 thieno[3,2-b]thiophene-2-carbaldehyde 
• 1202258-29-4 1,4-dihydro-2,6-dimethyl-4-(3'-methyl 2-thioacetate-thiophen-2'-yl)-pyridine-3,5-dicarboxylic acid dibenzyl ester 
• 1202258-33-0 1,4-dihydro-2,6-dimethyl-4-(3'-methyl 2-thioacetate-thiophen-2'-yl)pyridine-3-carboxylic acid benzyl ester 5-carboxylic acid ethyl ester 

Relevant articles and documents

New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-Substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted theio[3,2-b]thiophene-2-sulfonamides

A series of 5-substituted thieno[2,3-b]- and thieno[3,2-b]thiophene-2-sulfonamides was prepared and evaluated for topical ocular hypotensive activity in glaucoma models. The 5-substituents were varied to maximize both inhibitory potency against carbonic anhydrase and water solubility. At the same time, these substituents were varied in order to obtain compounds with the appropriate pK(a) to minimize pigment binding in the iris. All of these variables were optimized in the best compound, 5-[[(methoxyethyl)](methoxyethyl)ethyl]amino]methyl]thieno[2,3-b] thiophene-2-sulfonamide hydrochloride (55).