172588-77-1Relevant articles and documents
SYNTHESIS AND APPLICATION OF CHIRAL SUBSTITUTED POLYVINYLPYRROLIDINONES
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Paragraph 0063, (2020/11/24)
Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.
Biocatalysis of Deracemization in 1,2-Diols
Page, Philip C. Bulman,Carnell, Andrew J.,McKenzie, Michael J.
, p. 774 - 776 (2007/10/03)
The fungus Corynosporium cassicola DSM 62475 is shown to induce deracemization in certain 1,2-diols, including the synthetically important indane-1,2-diol, by enantioconvergent stereoinversion processes in which the recovered enantiomer is not a substrate for the dehydrogenase enzymes involved.
Microbiological transformations 32: Use of epoxide hydrolase mediated biohydrolysis as a way to enantiopure epoxides and vicinal diols: Application to substituted styrene oxide derivatives
Pedragosa-Moreau,Archelas,Furstoss
, p. 4593 - 4606 (2007/10/03)
The biohydrolyses of various substituted styrene oxide derivatives using the fungi Aspergillus niger or Beauveria sulferescens are described. The results obtained show that this methodology allows the preparation of enantiomerically enriched epoxides and diols via enantioselective and regioselective hydration. The comparative study of the results obtained suggests that these hydrolyses operate following different mechanisms and a model of the corresponding active sites is proposed.