172648-19-0 Usage
General Description
The chemical "(6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol" is an organic compound with a molecular formula of C8H7BrN2O. It is a white to off-white solid that is used as a building block in the synthesis of pharmaceutical and agrochemical compounds. This chemical is known for its potential biological activities and is often used in research and development of new drugs and agrochemicals. It is important to handle this compound with care and follow proper safety protocols in its handling and storage.
Check Digit Verification of cas no
The CAS Registry Mumber 172648-19-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,2,6,4 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 172648-19:
(8*1)+(7*7)+(6*2)+(5*6)+(4*4)+(3*8)+(2*1)+(1*9)=150
150 % 10 = 0
So 172648-19-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H6BrN3O/c8-4-1-5-7(9-2-4)11-6(3-12)10-5/h1-2,12H,3H2,(H,9,10,11)
172648-19-0Relevant articles and documents
Molecular design, synthesis, and hypoglycemic activity of a series of thiazolidine-2,4-diones
Oguchi,Wada,Honma,Tanaka,Kaneko,Sakakibara,Ohsumi,Serizawa,Fujiwara,Horikoshi,Fujita
, p. 3052 - 3066 (2007/10/03)
A series of imidazopyridine thiazolidine-2,4-diones were designed and synthesized from their corresponding pyridines. These compounds represent conformationally restricted analogues of the novel hypoglycemic compound rosiglitazone (5). The series was evaluated for its effect on insulin-induced 3T3-L1 adipocyte differentiation in vitro and its hypoglycemic activity in the genetically diabetic KK mouse in vivo. The structure-activity relationships are discussed. On the basis of the in vivo potency, 5-[4-(5-methoxy-3-methyl-3H-imidazo[4,5-b]pyridin-2-ylmethoxy)ben zyl]thiazolidine-2,4-dione (19a) was selected as the candidate for further studies in a clinical setting.
