17266-64-7

Basic information

• Product Name: 1H-Pyrrolizin-1-one,2,3-dihydro-(6CI,7CI,8CI,9CI)
• Synonyms: 1H-Pyrrolizin-1-one,2,3-dihydro-(6CI,7CI,8CI,9CI);3H-1,2-dihydro-1-pyrrolizinone;2,3-Dihydro-1H-pyrrolizine-1-one
• CAS NO: 17266-64-7
• Molecular Formula: C₇H₇NO
• Molecular Weight: 121.14
• Product Categories: PYRROLIDINE;AMINETERTIARY;Aromatics, Heterocycles, Miscellaneous Reagents
• Mol File: 17266-64-7.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 231.1°Cat760mmHg
• Flash Point: 93.5°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 0.0636mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: 1H-Pyrrolizin-1-one,2,3-dihydro-(6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolizin-1-one,2,3-dihydro-(6CI,7CI,8CI,9CI)(17266-64-7)
• EPA Substance Registry System: 1H-Pyrrolizin-1-one,2,3-dihydro-(6CI,7CI,8CI,9CI)(17266-64-7)

Safety Data

• Hazardous Substances Data: 17266-64-7(Hazardous Substances Data)

Usage

Description

1H-Pyrrolizin-1-one,2,3-dihydro-(6CI,7CI,8CI,9CI), also known as 2,3-Dihydro-1H-pyrrolizine-1-one, is an organic compound with a unique chemical structure that features a pyrrole ring fused to a pyrrolizinone moiety. 1H-Pyrrolizin-1-one,2,3-dihydro-(6CI,7CI,8CI,9CI) is of interest in the field of organic chemistry and pharmaceutical research due to its potential applications in the synthesis of various compounds.

Uses

1. Used in Pharmaceutical Research:
1H-Pyrrolizin-1-one,2,3-dihydro-(6CI,7CI,8CI,9CI) is used as an intermediate in the synthesis of cannabinoid analogues with pyrrole moieties. These analogues have potential applications in the development of new drugs targeting the endocannabinoid system, which plays a crucial role in various physiological processes and is associated with a range of therapeutic indications, including pain management, inflammation, and neurological disorders.
2. Used in Chemical Synthesis:
In the chemical industry, 1H-Pyrrolizin-1-one,2,3-dihydro-(6CI,7CI,8CI,9CI) can be utilized as a building block for the synthesis of more complex organic molecules with potential applications in various fields, such as materials science, agrochemistry, and pharmaceuticals. Its unique structure and reactivity make it a valuable component in the development of novel compounds with specific properties and functions.

InChI:InChI=1/C7H7NO/c9-7-3-5-8-4-1-2-6(7)8/h1-2,4H,3,5H2

Upstream product

• 43036-06-2 3-(pyrrol-1-yl)propanenitrile 
• 60-29-7 diethyl ether 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 201230-82-2 carbon monoxide 
• 280783-30-4 1-(2-bromo-ethyl)-2-methanesulfonyl-1H-pyrrole 
• 89059-06-3 N-(2-carboxyethyl)pyrrole 
• 99233-38-2 methyl 3-(1-pyrrolidyl)propionate 

Downstream Products

• 1009375-96-5 2-[(E)-(4-fluorophenyl)methylidene]-2,3-dihydro-1H-pyrrolizin-1-one 
• 1415034-40-0 6-chloro-1-(2,4-dichlorophenyl)-N-(piperidin-1-yl)-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxamide 
• 1415034-39-7 1-(2,4-dichlorophenyl)-6-methyl-N-(piperidin-1-yl)-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxamide 
• 1415034-38-6 6-chloro-1-(2,4-dichlorophenyl)-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxylic acid 

Relevant articles and documents

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SUBSTITUTED TETRAHYDROCYCLOPENTA[C]PYRROLES, SUBSTITUTED DIHYDROPYRROLIZINES, ANALOGUES THEREOF, AND METHODS USING SAME

The present invention includes novel substituted bicyclic compounds, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infection and/or hepatitis D virus (HDV) infection in a patient.

DIHYDROINDOLIZINE DERIVATE AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS

The invention relates to heterocyclic derivatives of formula I, wherein the substituents R1-R5 and R11 are as defined in the claims, as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are mGluR5 modulators and are therefore useful for the control and prevention of acute and/or chronic neurological disorders.