172843-10-6

Basic information

• Product Name: 1,3-bis[[tert-butyl(diphenyl)silyl]oxy]propan-2-one
• Synonyms: 1,3-bis[[tert-butyl(diphenyl)silyl]oxy]propan-2-one
• CAS NO: 172843-10-6
• Molecular Weight: 566.888
• Mol File: 172843-10-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,3-bis[[tert-butyl(diphenyl)silyl]oxy]propan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis[[tert-butyl(diphenyl)silyl]oxy]propan-2-one(172843-10-6)
• EPA Substance Registry System: 1,3-bis[[tert-butyl(diphenyl)silyl]oxy]propan-2-one(172843-10-6)

Safety Data

• Hazardous Substances Data: 172843-10-6(Hazardous Substances Data)

Upstream product

• 96-26-4 dihydroxyacetone 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 320410-45-5 5-(2-benzyloxyethyl)-2,2-di(tert-butyldiphenylsilyloxymethyl)-1,3-dioxane 
• 357930-19-9 6-[2-[(1,3-bis-(tert-butyldiphenylsilyloxy)-2-hydroxy)propyl]methyl]-2,4-dimethoxy-5-methylpyrimidine 
• 528881-73-4 5,5-bis[(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)methyl]-3-(methylethylidene)-4,4-dihydrofuran-2-one 
• 1163691-97-1 C₄₉H₅₃F₃N₂O₅Si₂ 
• 172843-19-5 (Z)-5-bis<<(tert-butyldiphenylsilyl)oxy>methyl>-3-<(Z)-9-octadecenylidene>tetrahydro-2-furanone 
• 172843-24-2 (E)-5-bis<<(tert-butyldiphenylsilyl)oxy>methyl>-3-<(Z)-9-octadecenylidene>tetrahydro-2-furanone 
• 172843-18-4 5,5-Bis-(tert-butyl-diphenyl-silanyloxymethyl)-3-tetradec-(Z)-ylidene-dihydro-furan-2-one 
• 172843-23-1 5,5-Bis-(tert-butyl-diphenyl-silanyloxymethyl)-3-tetradec-(E)-ylidene-dihydro-furan-2-one 
• 172843-14-0 5-bis<<(tert-butyldiphenylsilyl)oxy>methyl>tetrahydro-2-furanone 
• 357930-21-3 6-[2-[(1,3-bis-(tert-butyldiphenylsilyloxy)-2-methylthiomethyloxy)propyl]methyl]-2,4-dimethoxy-5-methylpyrimidine 
• 357930-25-7 3,3-bis(tert-butyldiphenylsilyloxymethyl)-5-methyl-1H,3H,4H,7H-pyrimido[1,6-c][1,3]oxazine-6,8-dione 
• 357930-23-5 3,3-bis(tert-butyldiphenylsilyloxymethyl)-6-methoxy-5-methyl-1H,3H,4H-pyrimido[1,6-c][1,3]oxazine-8-one 
• 453508-95-7 2-(5-tert-butyldiphenylsiloxy-4-tert-butyldiphenylsiloxymethyl-4-hydroxypentyl)-2-methyl-1,3-dioxolane 
• 172843-12-8 2-hydroxy-2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1-<(tert-butyldiphenylsilyl)oxy>-4-pentene 

Relevant articles and documents

An improved synthetic preparation of anti conformationally constrained acyclic nucleosides

Practical large-scale synthesis of anti conformationally constrained acyclic nucleosides has been attained from the coupling of lithiated 2,4-dimethoxy-5,6-dimethylpyrimidine with 1,3-bis(tert-butyldiphenylsilyloxy)-propan-2-one, followed by the sequentia

PROTEIN KINASE C AGONISTS

The present disclosure relates generally to certain diacylglycerol lactone compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by protein kinase C (PKC) agonists, such as HIV.

VIRAL POLYMERASE INHIBITORS

Compounds of formula I: wherein X, R2, R3, R3a, R3b,R5 and R6 are defined herein, are useful as inhibitors of the hepatitis C virus NS5B polymerase.