172875-70-6

Basic information

• Product Name: Dehydro N2-TriphenylMethyl OlMesartan Ethyl Ester
• Synonyms: Dehydro N2-TriphenylMethyl OlMesartan Ethyl Ester
• CAS NO: 172875-70-6
• Molecular Formula: C₄₅H₄₂N₆O₂
• Molecular Weight: 698.85398
• Product Categories: Aromatics, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 172875-70-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Dehydro N2-TriphenylMethyl OlMesartan Ethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: Dehydro N2-TriphenylMethyl OlMesartan Ethyl Ester(172875-70-6)
• EPA Substance Registry System: Dehydro N2-TriphenylMethyl OlMesartan Ethyl Ester(172875-70-6)

Safety Data

• Hazardous Substances Data: 172875-70-6(Hazardous Substances Data)

Usage

Uses

Intermediate in the preparation of antihypertensive drugs.

Upstream product

• 172875-59-1 ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[2'-(2-triphenylmethyl-2H-tetrazol-5-yl)biphenyl-4-yl]methyl-1H-imidazole-5-carboxylate 
• 133051-88-4 N-(triphenylmethyl)-5-<4'-(bromomethyl)biphenyl-2-yl>tetrazole 
• 51802-42-7 2-propylimidazole-4,5-dicarbonitrile 
• 144689-93-0 ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylate 
• 144689-94-1 diethyl 2-(n-propyl)-1H-imidazole-4,5-dicarboxylate 
• 58954-23-7 2-propyl-1H-imidazole-4,5-dicarboxylic acid 
• 157356-73-5 ethyl 4-isopropenyl-2-propylimidazole-5-carboxylate 

Downstream Products

• 172875-87-5 5-Isopropenyl-2-propyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid ethyl ester 
• 172875-98-8 1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-4-(prop-1-en-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid 

Relevant articles and documents

Preparation method of high-purity triphenyl olmesartan ethyl ester

The invention provides a preparation method of a high-purity olmesartan medoxomil intermediate triphenyl olmesartan ethyl ester. The provided preparation method specifically comprises the steps that in a first solvent, in the presence of a combined catalyst and potassium carbonate, a compound shown in a formula 2 and a compound shown in a formula 3 react with each other to obtain a compound shownin a formula 1, wherein the combined catalyst is composed of polyethylene glycol and 2-methylpyrrolidone. The preparation method can significantly reduce the content of the impurities shown in a formula 4 and formula 5 in the product intermediate shown in the formula 1, and improve the purity of the intermediate shown in the formula 1.