172973-70-5Relevant articles and documents
New preparation method of 2-ethylbutyric acid
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Paragraph 0014, (2017/07/21)
The invention provides a new preparation method of 2-ethylbutyric acid. The preparation method includes the steps of: performing a reaction to propyl aldehyde and ethyl magnesium halide to prepare 3-pentanol; preparing 3-halogenated pentane from the 3-pentanol; preparing a Grignard reagent from the 3-halogenated pentane, and performing a reaction with CO2 to prepare the 2-ethylbutyric acid. The synthesis route is represented as follows. The method employs easy-to-obtained raw materials and is high in atom economy and low in industrial cost, thereby avoiding some defects in conventional methods.