173009-66-0Relevant articles and documents
Reaction kinetics and mechanism of acid-catalyzed anomerization of 1-O-acetyl-2,3,5-tri-O-benzoyl-l-ribofuranose
Forsman, Jonas J.,Waerna, Johan,Murzin, Dmitry Yu.,Leino, Reko
body text, p. 1102 - 1109 (2009/09/05)
The mechanism of the acid-catalyzed anomerization of 1-O-acetyl-2,3,5-O-benzoyl-α- and -β-l-ribofuranoses in different acetic acid-acetic anhydride mixtures was investigated. The progress of the reactions was followed by NMR spectroscopy and the rate cons
Synthesis of peracylated derivatives of L-ribofuranose from D-ribose and their use for the preparation of β-L-ribonucleosides
Sivets, Grigorii G.,Klennitskaya, Tatjana V.,Zhernosek, Elena V.,Mikhailopulo, Igor A.
, p. 253 - 259 (2007/10/03)
A practical synthesis of peracylated derivatives of β-L-ribofuranose 13-15 from D-ribose was accomplished in 6 steps (total yield: 30-45percent). Compound 13 was employed for the preparation of 1-(β-L-ribofuranosyl)thymine (16) and -cytosine (17), which are key intermediates for the preparation of the nucleoside derivatives with β-L-configuration. Simultaneous transformation of 17 into β-L-ddC (19) and β-L-3′dC (20) was studied.