1732-25-8

Basic information

• Product Name: Pyrene, 4-bromo-1,2,3,6,7,8-hexahydro-
• CAS NO: 1732-25-8
• Molecular Formula: C16H15Br
• Molecular Weight: 287.199
• Mol File: 1732-25-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Pyrene, 4-bromo-1,2,3,6,7,8-hexahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrene, 4-bromo-1,2,3,6,7,8-hexahydro-(1732-25-8)
• EPA Substance Registry System: Pyrene, 4-bromo-1,2,3,6,7,8-hexahydro-(1732-25-8)

Safety Data

• Hazardous Substances Data: 1732-25-8(Hazardous Substances Data)

Upstream product

• 129-00-0 pyrene 
• 75-15-0 carbon disulfide 
• 1732-13-4 1,2,3,6,7,8-hexahydropyrene 
• 7726-95-6 bromine 

Downstream Products

• 69795-73-9 3-hydroxy-3,4-dihydrocyclopentapyrene 
• 22245-55-2 pyren-4-ylacetic acid 
• 69795-70-6 cyclopentapyrene-3(4H)-one 
• 27208-37-3 cyclopenta[c,d]pyrene 
• 3353-12-6 4-methylpyrene 
• 1732-26-9 4-bromopyrene 

Relevant articles and documents

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A novel 4-hydroxypyrene-based “off–on” fluorescent probe with large Stokes shift for detecting cysteine and its application in living cells

This paper reports a novel fluorescent probe 4-acrylatepyrene (PYAC) based on 4-hydroxypyrene, which can effectively detect cysteine (Cys). The probe PYAC uses acrylate moiety as a recognition site and has relatively high selectivity and sensitivity for Cys with the detection limit of 0.062 μM. After treatment with Cys, PYAC exhibits “off–on” switching property and large Stokes shift (171 nm). Due to nucleophilic addition and specific intramolecular cyclization, it exhibits higher selectivity for Cys than other amino acids and common ions, including homocysteine (Hcy) and glutathione (GSH) with similar structures to Cys. The recognition mechanism has been characterized by high-performance liquid chromatography (HPLC) and nuclear magnetic resonance spectroscopy (1H NMR). Anti-interference test and pH influence test display it is suitable for detecting Cys in living cells. Finally, the probe PYAC has been successfully applied to cell imaging with negligible cytotoxicity.

Derivatised molecules for mass spectrometry

Compounds of formula (IIa): are provided where:X is a group capable of being cleaved from the α-carbon atom to form an ion of formula (I')C is a carbon atom bearing a single positive charge or a single negative charge; The invention further provides compounds of formula (IIb): where:X is a counter-ion to C. The compounds of formula (IIa) and (IIb) may form ions of formula (I') by either cleaving the C-X bond between X and the α-carbon atoms in the case of the compounds of formula (IIa) or dissociating X in the case of compounds of formula (IIb).