17361-44-3

Basic information

• Product Name: ditetradecylamine
• Synonyms: N-Tetradecyl-1-tetradecanamine;Alamine 205;Dimyristylamine;Di-n-tetradecylamine;N,N-Ditetradecylamine;NSC 91530
• CAS NO: 17361-44-3
• Molecular Formula: C₂₈H₅₉N
• Molecular Weight: 409.7748
• EINECS: 241-389-9
• Mol File: 17361-44-3.mol
• Article Data: 16

Chemical Properties

• Melting Point: 60.62°C
• Boiling Point: 449.95°C (estimate)
• Flash Point: 170.9 °C
• Appearance: /
• Density: 0.8452 (estimate)
• Vapor Pressure: 1.17E-09mmHg at 25°C
• Refractive Index: 1.4716 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: ditetradecylamine(CAS DataBase Reference)
• NIST Chemistry Reference: ditetradecylamine(17361-44-3)
• EPA Substance Registry System: ditetradecylamine(17361-44-3)

Safety Data

• Hazardous Substances Data: 17361-44-3(Hazardous Substances Data)

Usage

General Description

Ditetradecylamine is a long-chain alkylamine compound, consisting of two tetradecyl groups attached to a central amine group. It is commonly used as a surfactant and emulsifying agent in various industrial applications, including in the production of pesticides, corrosion inhibitors, and personal care products. Ditetradecylamine functions by lowering the surface tension of liquids and facilitating the mixing of non-miscible substances, making it valuable for formulating stable emulsions and suspensions. Additionally, it is an effective corrosion inhibitor, often used in the protection of metal surfaces in industrial settings. However, precautions should be taken when handling ditetradecylamine, as it can be irritating to the skin and eyes and may cause respiratory irritation if inhaled.

InChI:InChI=1/C28H59N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h29H,3-28H2,1-2H3

Upstream product

• 2016-42-4 tetradecylamine 
• 2425-54-9 myristyl chloride 
• 112-71-0 1-Bromotetradecane 
• 638-58-4 tetradecanamide 
• 159458-37-4 thiomyristamide 
• 622-56-0 myristanilide 
• 123-91-1 1,4-dioxane 
• 112-64-1 tetradecanoyl chloride 
• 544-63-8 n-tetradecanoic acid 
• 555-45-3 tritetradecanoylglycerol 
• 124-25-4 myristylaldehyde 

Downstream Products

• 128262-58-8 2,3-Dimethoxy-N,N-ditetradecyl-terephthalamic acid 
• 95634-16-5 N,N-ditetradecyl-Nε-benzyloxycarbonyl-L-lysinamide 
• 116058-83-4 N,N-ditetradecyl-Nα-<6-(trimethylammonio)hexanoyl>-Nε-benzyloxycarbonyl-L-lysinamide bromide 
• 116058-82-3 N,N-ditetradecyl-Nα-6-bromohexanoyl-Nε-benzyloxycarbonyl-L-lysinamide 
• 95634-16-5 N,N-ditetradecyl-N^ε-(benzyloxycarbonyl)-L-lysinamide 
• 83824-98-0 N,N-ditetradecyl-N^α-(6-bromohexanoyl)-L-histidinamide 
• 83824-99-1 (S)-2-Amino-N,N-ditetradecyl-3-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-propionamide 
• 848872-88-8 {2-[2-(2-ditetradecylcarbamoylmethoxy-acetylamino)-acetylamino]-acetylamino}-acetic acid benzyl ester 
• 122020-34-2 3-(2,4-Dimethyl-phenyl)-1,1-ditetradecyl-urea 
• 116058-81-2 N,N-ditetradecyl-Nα-t-butoxycarbonyl-Nε-benzyloxycarbonyl-L-lysinamide 
• 83824-97-9 N,N-ditetradecyl-N^α-t-butoxycarbonyl-N^im-tosyl-L-histidinamide 
• 129194-28-1 N,N-ditetradecyl-N^α-(tert-butoxycarbonyl)-L-isoasparagine β-benzyl ester 
• 128262-57-7 2,3-Dimethoxy-N,N-ditetradecyl-terephthalamic acid methyl ester 
• 41961-81-3 methyl-ditetradecyl-amine 

Relevant articles and documents

Serum Compatible Spermine-Based Cationic Lipids with Nonidentical Hydrocarbon Tails Mediate High Transfection Efficiency

Cationic lipids are widely used as nonviral synthetic vectors for gene delivery as a safer alternative to viral vectors. In this work, a library of L-shaped spermine-based cationic lipids with identical and nonidentical hydrophobic chains having variable carbon lengths (from C10 to C18) was designed and synthesized. These lipids were characterized and the structure-activity relationships of these compounds were determined for DNA binding and transfection ability when formulated as cationic liposomes. The liposomes were then used successfully for the transfection of HEK293T, HeLa, PC3, H460, HepG2, SH-SY5Y and Calu’3 cell lines. The transfection efficiency of lipids with nonidentical hydrocarbon chains was greater than the identical analogue. These reagents exhibited superior efficiency to the commercial reagent, Lipofectamine3000, under both serum-free and 10–40 % serum conditions in HEK293T, HeLa and H460 cell lines. The lipids were not toxic to the tested cell line. The results suggest that L-shaped spermine-based cationic lipids with nonidentical hydrocarbon tails could serve as efficient and safe nonviral vector gene carriers in further in vivo studies.

Selective Transformations of Triglycerides into Fatty Amines, Amides, and Nitriles by using Heterogeneous Catalysis

The use of triglycerides as an important class of biomass is an effective strategy to realize a more sustainable society. Herein, three heterogeneous catalytic methods are reported for the selective one-pot transformation of triglycerides into value-added chemicals: i) the reductive amination of triglycerides into fatty amines with aqueous NH3 under H2 promoted by ZrO2-supported Pt clusters; ii) the amidation of triglycerides under gaseous NH3 catalyzed by high-silica H-beta (Hβ) zeolite at 180 °C; iii) the Hβ-promoted synthesis of nitriles from triglycerides and gaseous NH3 at 220 °C. These methods are widely applicable to the transformation of various triglycerides (C4–C18 skeletons) into the corresponding amines, amides, and nitriles.

LIPID NANOPARTICLE FORMULATIONS

Improved formulations of lipid nanoparticles are provided. Use of the lipid nanoparticles for delivery of a therapeutic agent and methods for their preparation are also provided.