17388-70-4

Basic information

• Product Name: Z-TRP-GLY-OH
• Synonyms: Z-TRP-GLY-OH;Z-L-TRYPTOPHYL-GLYCINE
• CAS NO: 17388-70-4
• Molecular Formula: C₂₁H₂₁N₃O₅
• Molecular Weight: 395.41
• Mol File: 17388-70-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 773.1°Cat760mmHg
• Flash Point: 421.3°C
• Appearance: /
• Density: 1.358g/cm³
• Vapor Pressure: 3.8E-25mmHg at 25°C
• Refractive Index: 1.65
• Storage Temp.: -15°C
• CAS DataBase Reference: Z-TRP-GLY-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-TRP-GLY-OH(17388-70-4)
• EPA Substance Registry System: Z-TRP-GLY-OH(17388-70-4)

Safety Data

• Hazardous Substances Data: 17388-70-4(Hazardous Substances Data)

Usage

General Description

Z-TRP-GLY-OH is a chemical compound that consists of the amino acids L-tryptophan (TRP) and glycine (GLY), and is capped with a Z group at the N-terminus and a carboxylic acid group at the C-terminus. L-tryptophan is an essential amino acid that plays a crucial role in protein synthesis, serotonin production, and regulation of mood and sleep. Glycine is a nonessential amino acid that is important for the synthesis of proteins, enzymes, and other molecules in the body. The Z-TRP-GLY-OH compound may have potential applications in pharmaceutical research and development due to the amino acids' biological activities and their ability to influence various biological pathways.

InChI:InChI=1/C21H21N3O5/c25-19(26)12-23-20(27)18(10-15-11-22-17-9-5-4-8-16(15)17)24-21(28)29-13-14-6-2-1-3-7-14/h1-9,11,18,22H,10,12-13H2,(H,23,27)(H,24,28)(H,25,26)

Upstream product

• 2279-10-9 Z-Trp-Gly-OMe 
• 56-40-6 glycine 
• 64693-64-7 N^α-benzyloxycarbonyl-L-tryptophyl chloride 
• 50305-28-7 Cbz-L-Tryptophan-OSu 
• 850232-59-6 benzyl N-[(1S)-2-(1H-1,2,3-benzotriazol-1-yl)-1-(1H-indol-3-ylmethyl)-2-oxoethyl]carbamate 
• 73-22-3 L-Tryptophan 
• 501-53-1 benzyl chloroformate 
• 7432-21-5 N-carbobenzyloxy-L-tryptophane 
• 16624-64-9 N-α-carbobenzoxy-L-tyrosine p-nitrophenyl ester 

Downstream Products

• 112689-73-3 N-L-tryptophyl-glycine benzyl ester; hydrochloride 
• 1173817-67-8 benzyl N-((1S)-2-[2-(1H-1,2,3-benzotriazol-1-yl)-2-oxoethyl]amino-1-(1H-indol-2-ylmethyl)-2-oxoethyl)carbamate 
• 68996-89-4 benzyl N-[(1S)-2-[(2-amino-2-oxoethyl)amino]-1-(1H-indol-2-ylmethyl)-2-oxoethyl]carbamate 
• 75511-61-4 C₅₃H₇₃N₁₃O₁₄S₂ 
• 75511-59-0 (benzyloxycarbonyl)-L-prolyl-L-tryptophylglycinamide 
• 38689-27-9 H-Trp-Gly-CONH₂ 
• 195522-02-2 Z-Ser(Bu^t)-Trp-Gly-OH 
• 7360-09-0 L-tryptophyl-Glycine 

Relevant articles and documents

Convenient synthesis of C-terminal di- and tri-peptide amides from N-protected dipeptidoylbenzotriazoles

N-Protected dipeptidoylbenzotriazoles react with aqueous ammonia to give dipeptide primary amides (77-98%) and with N-unprotected α-amino amides to afford tripeptide primary amides (82-86%).

SYNTHESIS AND EVALUATION OF ANTIGENIC PROPERTIES OF PEPTIDES OF THE HIV-1 PROTEIN GP 41

Scheme is described for the synthesis of 19- and 21-member peptides which constitute a part of the domain (sequence 584-609) from the conservative region of the transmembrane protein gp 41 HIV-1.The synthesis was carried out using standard methods of pept