173912-66-8

Basic information

• Product Name: 3-fluoro-4-nitro-N--L-phenylalanine methyl ester
• Synonyms: 3-fluoro-4-nitro-N--L-phenylalanine methyl ester
• CAS NO: 173912-66-8
• Molecular Weight: 505.5
• Mol File: 173912-66-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-fluoro-4-nitro-N--L-phenylalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-fluoro-4-nitro-N--L-phenylalanine methyl ester(173912-66-8)
• EPA Substance Registry System: 3-fluoro-4-nitro-N--L-phenylalanine methyl ester(173912-66-8)

Safety Data

• Hazardous Substances Data: 173912-66-8(Hazardous Substances Data)

Upstream product

• 3978-80-1 Boc-Tyr-OH 
• 160247-84-7 (2S,5R)-2-(3'-fluoro-4'-nitrobenzyl)-5-isopropyl-3,6-dimethoxy-2,5-dihydropyrazine 
• 131858-37-2 4-(bromomethyl)-2-fluoro-1-nitrobenzene 
• 113807-07-1 L-BOC-Tyr-OC₆F₅ 
• 160247-85-8 (S)-3-fluoro-4-nitrophenylalanine methyl ester 

Relevant articles and documents

A new approach to the synthesis of piperazinomycin and bouvardin: Facile access to cycloisodityrosine via an intramolecular SNAr reaction

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Synthesis of (9S,12S)-cycloisodityrosine and its unnatural (9R,12S)- diastereomer

A synthesis of the (9S,12S)-cycloisodityrosine derivatives and their unnatural (9R,12S)-diastereomers are disclosed. The approach is based on an intramolecular aromatic nucleophilic substitution reaction for formation of the macrocyclic biaryl ether and includes the documentation of a remarkably facile base-catalyzed epimerization.