174075-99-1

Basic information

• Product Name: tert-butyl α-fluoro-α-(triisopropylsilyl)acetate
• Synonyms: tert-butyl α-fluoro-α-(triisopropylsilyl)acetate
• CAS NO: 174075-99-1
• Molecular Weight: 290.494
• Mol File: 174075-99-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl α-fluoro-α-(triisopropylsilyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl α-fluoro-α-(triisopropylsilyl)acetate(174075-99-1)
• EPA Substance Registry System: tert-butyl α-fluoro-α-(triisopropylsilyl)acetate(174075-99-1)

Safety Data

• Hazardous Substances Data: 174075-99-1(Hazardous Substances Data)

Upstream product

• 406-74-6 tert-butyl α-fluoroacetate 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 

Relevant articles and documents

Fluoroolefin containing dipeptide isosteres as inhibitors of dipeptidyl peptidase IV(CD26)

(Z)-(S)Ala-Ψ[CF = C]-(RS)-Pro containing N,O-diacylhydroxamic acid type protease inhibitors have been prepared for the study of the influence of propylamide bond geometry on the inhibition of dipeptidyl peptidase IV(CD26). The synthesis is based upon the use of tert-butyl-α-fluoro-α-trimethylsilylacetate in a variation of the Peterson olefination procedure to construct the necessary functionalized fluoroolefin.