17437-24-0Relevant articles and documents
Direct interaction, instrumental for signaling processes, between LacCer and Lyn in the lipid rafts of neutrophil-like cells
Chiricozzi, Elena,Ciampa, Maria Grazia,Brasile, Giuseppina,Compostella, Federica,Prinetti, Alessandro,Nakayama, Hitoshi,Ekyalongo, Roudy C.,Iwabuchi, Kazuhisa,Sonnino, Sandro,Mauri, Laura
, p. 129 - 141 (2015/03/05)
Lactosylceramide [LacCer; β-Gal-(1-4)-β-Glc-(1-1)-Cer] has been shown to contain very long fatty acids that specifically modulate neutrophil properties. The interactions between LacCer and proteins and their role in cell signaling processes were assessed
ALBUMIN-BINDING COMPOUNDS
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Page/Page column 31-32, (2010/02/15)
The present invention provides an albumin-binding compound essentially of the following elements: a spacer group, a water-soluble bridging group, a fatty acid chain and an acidic group characterised in that the acidic group is attached to the distal end of the fatty acid chain. The invention also provides an albumin-binding compound to which one or more biologically active moieties are attached.
Superoxide dismutase derivatives
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, (2008/06/13)
Provided are novel superoxide dismutase derivatives represented by the following general formula (I) wherein [SOD] is a superoxide dismutase residue derived by removal of two mercapto groups, and W is a divalent long chain hydrocarbon residue which may optionally be interrupted by one or more groups each independently selected from the group consisting of an oxygen atom, a sulfur atom and a group of -N(R)- (R being a lower alkyl group). The SOD derivatives retain most of the enzymatic activities of unmodified SOD and have much longer plasma half-life than unmodified SOD. They are effective for treating various diseases caused by active oxygen species. Also provided are chemical modifiers to prepare the above SOD derivatives.