174715-24-3Relevant articles and documents
C(sp3)-H Monoarylation of Methanol Enabled by a Bidentate Auxiliary
Gou, Quan,Ran, Man,Ren, Jian,Tan, Xiaoping,Yuan, Binfang,Yuan, Tengrui,Zhang, Ming-Zhong,Zhang, Xing
supporting information, p. 118 - 123 (2021/01/13)
With the assistance of a practical directing group (COAQ), the first catalytic protocol for the palladium-catalyzed C(sp3)-H monoarylation of methanol has been developed, offering an invaluable synthesis means to establish extensive derivatives of crucial arylmethanol functional fragments. Furthermore, the gram-scale reaction, broad substrate scope, excellent functional group compatibility, and even the practical synthesis of medicines further demonstrate the usefulness of this strategy.
B(C6F5)3-Catalyzed Highly Chemoselective Reduction of Isatins: Synthesis of Indolin-3-ones and Indolines
Jeong, Hyojin,Han, Nara,Hwang, Dong Wook,Ko, Haye Min
supporting information, p. 8150 - 8155 (2020/11/02)
A chemo- and site-selective reduction reaction of isatin derivatives using catalyst B(C6F5)3 and hydrosilanes is described. This transformation is operationally simple, proceeds under mild conditions, and is resistant to various functional groups. Thus, this efficient reaction using a combination of B(C6F5)3 and BnMe2SiH or B(C6F5)3 and Et2SiH2 could potentially be utilized to produce various indolin-3-ones and indolines, without the need for multistep procedures and metal catalysis conditions.
Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds
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Paragraph 0131, (2019/07/03)
Methods of synthesizing compounds using CO2 as a directing group for C—H functionalization, and compounds made thereby, are described.
