174768-06-0

Basic information

• Product Name: (S)-2-{2-[(1-Benzyloxycarbonylamino-2-naphthalen-2-yl-ethyl)-methoxy-phosphinoylmethyl]-4-methyl-pentanoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester
• CAS NO: 174768-06-0
• Molecular Weight: 711.795
• Mol File: 174768-06-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-{2-[(1-Benzyloxycarbonylamino-2-naphthalen-2-yl-ethyl)-methoxy-phosphinoylmethyl]-4-methyl-pentanoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-{2-[(1-Benzyloxycarbonylamino-2-naphthalen-2-yl-ethyl)-methoxy-phosphinoylmethyl]-4-methyl-pentanoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester(174768-06-0)
• EPA Substance Registry System: (S)-2-{2-[(1-Benzyloxycarbonylamino-2-naphthalen-2-yl-ethyl)-methoxy-phosphinoylmethyl]-4-methyl-pentanoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester(174768-06-0)

Safety Data

• Hazardous Substances Data: 174768-06-0(Hazardous Substances Data)

Upstream product

• 174768-05-9 2-[(1-Benzyloxycarbonylamino-2-naphthalen-2-yl-ethyl)-methoxy-phosphinoylmethyl]-4-methyl-pentanoic acid 3,4-dimethoxy-benzyl ester 
• 4299-70-1 L-tryptophan methyl ester 
• 3857-83-8 2-naphthyl triflate 
• 174768-02-6 [1-(Benzhydryl-amino)-2-naphthalen-2-yl-ethyl]-phosphinic acid 
• 174768-04-8 (1-Benzyloxycarbonylamino-2-naphthalen-2-yl-ethyl)-phosphinic acid methyl ester 
• 174768-03-7 (1-Benzyloxycarbonylamino-2-naphthalen-2-yl-ethyl)-phosphinic acid 
• 174767-45-4 4-Methyl-2-methylene-pentanoic acid 3,4-dimethoxy-benzyl ester 
• 180027-51-4 (E)-2-(naphthalen-2-yl)vinyl acetate 
• 135-19-3 β-naphthol 
• 4361-06-2 isobutylmalonic Acid 
• 25044-10-4 2-methylene-4-methyl-pentanoic acid 

Relevant articles and documents

Highly potent and selective inhibitors of endothelin converting enzyme

Phosphinic acid derivatives, represented by structure 1, have been synthesized and evaluated as endothelin convening enzyme (ECE) inhibitors. Several of these compounds (for example, 1b, 1c, and 1f) were found to be potent inhibitors of ECE with a high degree of selectivity against neutral endopeptidase (NEP).