174867-64-2

Basic information

• Product Name: (3,4-dichlorophenoxy)methyl 2-(1-hydroxy-1-methylethyl)-4-methylphenyl methyl phosphate
• CAS NO: 174867-64-2
• Molecular Weight: 435.241
• Mol File: 174867-64-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3,4-dichlorophenoxy)methyl 2-(1-hydroxy-1-methylethyl)-4-methylphenyl methyl phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: (3,4-dichlorophenoxy)methyl 2-(1-hydroxy-1-methylethyl)-4-methylphenyl methyl phosphate(174867-64-2)
• EPA Substance Registry System: (3,4-dichlorophenoxy)methyl 2-(1-hydroxy-1-methylethyl)-4-methylphenyl methyl phosphate(174867-64-2)

Safety Data

• Hazardous Substances Data: 174867-64-2(Hazardous Substances Data)

Upstream product

• 6627-55-0 2-bromo-p-cresol 
• 174867-49-3 2-<1-(benzyloxymethoxy)-1-methylethyl>-4-methylphenyl dimethyl phosphate 
• 174867-46-0 2-(1-hydroxy-1-methylethyl)-4-methylphenyl tert-butyldimethylsilylether 
• 78719-73-0 2-Hydroxy-α,α,5-trimethylbenzyl alcohol 
• 174867-52-8 (3,4-dichlorophenoxy)methyl 2-<1-(benzyloxymethoxy)-1-methylethyl>-4-methylphenyl methyl phosphate 
• 174867-47-1 2-<1-(benzyloxymethoxy)-1-methylethyl>-4-methylphenyl tert-butyldimethylsilylether 
• 174867-48-2 2-<1-(benzyloxymethoxy)-1-methylethyl>-4-methylphenol 

Downstream Products

• 7361-70-8 methyl 2-chloro-4-nitrophenyl phosphate 
• 174867-53-9 methyl 2-(1-hydroxy-1-methylethyl)-4-methylphenol cyclic phosphate 

Relevant articles and documents

Rapid intramolecular and C-O cleavage reactions of a phosphate triester catalysed by a neighbouring hydroxyl group

Three consecutive reactions are observed when the phosphate triester 6 is hydrolysed. At pH 12 M. 12 is then hydrolysed by C-O cleavage to give the diester 11. In base, the first two reactions are complete almost instantaneously, and the final phosphorus-containing products are (3,4-dichlorophenoxy)methyl methyl phosphate diester, and the methyl phosphate dianion. These must come from C-O cleavage reactions of diester 14 and the rearranged benzylic triester 15, which rapidly eliminate phosphate ester leaving groups to give the same quinone methide.