174906-30-0

Basic information

• Product Name: methyl (S)-N-benzyl-L-tyrosinate
• Synonyms: methyl (S)-N-benzyl-L-tyrosinate
• CAS NO: 174906-30-0
• Molecular Weight: 285.343
• Mol File: 174906-30-0.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: methyl (S)-N-benzyl-L-tyrosinate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (S)-N-benzyl-L-tyrosinate(174906-30-0)
• EPA Substance Registry System: methyl (S)-N-benzyl-L-tyrosinate(174906-30-0)

Safety Data

• Hazardous Substances Data: 174906-30-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1080-06-4 L-Tyr-OMe 
• 100-47-0 benzonitrile 
• 144-55-8 sodium hydrogencarbonate 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 100-52-7 benzaldehyde 
• 69955-04-0 methyl N-benzylidene-tyrosinate 
• 75768-66-0 L-N-(benzyl)-tyrosine 

Downstream Products

• 145242-43-9 L-N-benzyl-N-benzyloxycarbonyltyrosine methyl ester 
• 1638677-54-9 methyl (S)-2-(N-benzylpivalamido)-3-(4-(2-(4-methoxyphenyl)-2-oxoethyl)phenyl)propanoate 
• 1638677-55-0 methyl (S)-2-(N-benzylpivalamido)-3-(4-(2-(1-methyl-1H-indol-3-yl)-2-oxoethyl)phenyl)propanoate 
• 1638677-39-0 (S)-4-(2-(N-benzylpivalamido)-3-methoxy-3-oxopropyl)phenyl pivalate 
• 188446-17-5 (9S,12S)-12-(Benzyl-tert-butoxycarbonyl-amino)-4-nitro-11-oxo-2-oxa-10-aza-tricyclo[12.2.2.1^3,7]nonadeca-1⁽¹⁷⁾,3,5,7⁽¹⁹⁾,14⁽¹⁸⁾,15-hexaene-9-carboxylic acid methyl ester 
• 137622-55-0 (S)-2-(Benzyl-tert-butoxycarbonyl-amino)-3-(4-hydroxy-phenyl)-propionic acid 
• 70963-39-2 N-methyl-L-tyrosine methyl ester 
• 866392-22-5 N-benzyl-N-methyl-L-tyrosine methyl ester 
• 145242-42-8 (S)-N-benzyl-N-benzyloxycarbonyltyrosine 

Relevant articles and documents

A Bioinspired Synthesis of Polyfunctional Indoles

Polyfunctional indoles bearing substituents at C5 and C6 are prevalent in natural products, pharmaceuticals, agrochemicals, and materials. Owing to the remoteness of the C5 and C6 positions, indoles of this family can be difficult to prepare, and often require multistep syntheses. Herein, we describe a concise process that converts simple derivatives of tyrosine into 5,6-difunctionalized indoles by direct oxidation of C?H, N?H, and O?H bonds. Our work draws inspiration from the biosynthetic polymerization of tyrosine to make melanin pigments, but makes an important departure to provide well-defined indole heterocycles.

Mild and Selective Cobalt-Catalyzed Chemodivergent Transfer Hydrogenation of Nitriles

Herein, we describe a selective cobalt-catalyzed chemodivergent transfer hydrogenation of nitriles to synthesize primary, secondary, and tertiary amines. The solvent effect plays a key role for the selectivity control. The general applicability of this procedure was highlighted by the synthesis of more than 70 amine products bearing various functional groups in high chemoselectivity. Moreover, this mild system achieved >2000 TONs (turnover numbers) for the transfer hydrogenation of nitriles.

LIGAND, NICKEL COMPLEX COMPRISING LIGAND, AND REACTION USING NICKEL COMPLEX

PROBLEM TO BE SOLVED: To provide a method for directly carrying out arylation, especially α-arylation, of a carbonyl compound or a thiocarbonyl compound by using a more inexpensive phenol derivative and a nickel catalyst, and to provide a novel nickel cat