175069-96-2

Basic information

• Product Name: [HIS19]-CHARYBDOTOXIN
• Synonyms: [HIS19]-CHARYBDOTOXIN
• CAS NO: 175069-96-2
• Molecular Formula: C176H272N56O55S7
• Molecular Weight: 4276.84
• Product Categories: Ion Channel Modulating Peptides;Peptides for Cell Biology;Potassium Channel Modulators
• Mol File: 175069-96-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: [HIS19]-CHARYBDOTOXIN(CAS DataBase Reference)
• NIST Chemistry Reference: [HIS19]-CHARYBDOTOXIN(175069-96-2)
• EPA Substance Registry System: [HIS19]-CHARYBDOTOXIN(175069-96-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 175069-96-2(Hazardous Substances Data)

Usage

Description

[HIS19]-CHARYBDOTOXIN is a peptide toxin derived from the venom of the scorpion Leiurus quinquestriatus. It is a potent inhibitor of certain voltage-gated potassium channels, particularly the Kv1.3 subtype. This toxin is of interest because it has shown potential therapeutic applications for autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and type 1 diabetes. Additionally, [HIS19]-CHARYBDOTOXIN has been studied for its ability to modulate pain perception and as a tool for investigating the role of potassium channels in cellular physiology. Its unique structural and functional properties make it a valuable compound for understanding the mechanisms of ion channel regulation and for developing novel therapeutic interventions.

Uses

Used in Pharmaceutical Industry:
[HIS19]-CHARYBDOTOXIN is used as a therapeutic agent for autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and type 1 diabetes. It targets the Kv1.3 subtype of voltage-gated potassium channels, which play a role in the pathophysiology of these conditions, and can help modulate the immune response.
Used in Pain Management:
[HIS19]-CHARYBDOTOXIN is used as an analgesic agent for modulating pain perception. Its ability to interact with potassium channels can influence the transmission of pain signals, offering a potential approach for managing chronic pain conditions.
Used in Research Applications:
[HIS19]-CHARYBDOTOXIN is used as a research tool for investigating the role of potassium channels in cellular physiology. Its potent inhibitory effect on specific ion channels allows scientists to study the mechanisms of ion channel regulation and their involvement in various physiological processes.
Used in Drug Development:
[HIS19]-CHARYBDOTOXIN is used as a lead compound in the development of novel therapeutic interventions. Its unique structural and functional properties provide insights into the design of new drugs targeting ion channels, which can be applied to treat a range of diseases and conditions.