175136-82-0

Basic information

• Product Name: 2-CHLORO-6-FLUOROBENZYLIDENEACETONE
• Synonyms: LABOTEST-BB LT00455271;4-(2-CHLORO-6-FLUOROPHENYL)-3-BUTEN-2-ONE;4-(2-CHLORO-6-FLUOROPHENYL)BUT-3-EN-2-ONE;2-CHLORO-6-FLUOROBENZYLIDENEACETONE;1-(2-CHLORO-6-FLUOROPHENYL)BUT-1-EN-3-ONE;1-(2-Chloro-6-fluorophenyl)-1-buten-2-one;1-(2-Chloro-6-fluorophenyl)but-1-en-3-one 97%;1-(2-Chloro-6-fluorophenyl)but-1-en-3-one97%
• CAS NO: 175136-82-0
• Molecular Formula: C10H8ClFO
• Molecular Weight: 198.62
• EINECS: -0
• Mol File: 175136-82-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 115°C 0,8mm
• Flash Point: 115°C/0.8mm
• Appearance: /
• Density: 1.239 g/cm³
• Vapor Pressure: 0.00195mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 2-CHLORO-6-FLUOROBENZYLIDENEACETONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-FLUOROBENZYLIDENEACETONE(175136-82-0)
• EPA Substance Registry System: 2-CHLORO-6-FLUOROBENZYLIDENEACETONE(175136-82-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• HazardClass: IRRITANT
• Hazardous Substances Data: 175136-82-0(Hazardous Substances Data)

Usage

General Description

2-CHLORO-6-FLUOROBENZYLIDENEACETONE is a chemical compound with the molecular formula C10H8ClFO. It is a yellow crystalline solid that is commonly used in the synthesis of pharmaceuticals and fine chemicals. 2-CHLORO-6-FLUOROBENZYLIDENEACETONE is known for its potent antimicrobial and antifungal properties, and it is used in the development of new drugs and treatments for various diseases. Additionally, 2-CHLORO-6-FLUOROBENZYLIDENEACETONE has been studied for its potential as a pesticide and has shown promising results in agricultural applications. Overall, this compound has a wide range of potential uses in the fields of medicine, agriculture, and biotechnology.

InChI:InChI=1/C10H8ClFO/c1-7(13)5-6-8-9(11)3-2-4-10(8)12/h2-6H,1H3/b6-5+

Upstream product

• 387-45-1 2-chloro-6-fluorobenzaldehyde 
• 67-64-1 acetone 

Downstream Products

• 1597410-57-5 (E)-S-methyl 4-(2-chloro-6-fluorophenyl)-2-oxobut-3-enethioate 

Relevant articles and documents

Dehydrozingerone Inspired Discovery of Potential Broad-Spectrum Fungicidal Agents as Ergosterol Biosynthesis Inhibitors

A series of dehydrozingerone derivatives were synthesized, and their fungicidal activities and action mechanism against Colletotrichum musae were evaluated. The bioassay result showed that most compounds exhibited excellent fungicidal activity in vitro at 50 μg mL-1. Compounds 13, 16, 18, 19, and 27 exhibited broad-spectrum fungicidal activity; especially, compounds 19 and 27 were found to have more potent fungicidal activity than azoxystrobin. The EC50 values of compounds 19 and 27 against Rhizoctonia solani were 0.943 and 0.161 μg mL-1 respectively. Moreover, compound 27 exhibited significant in vitro bactericidal activity against Xanthomonas oryzae pv. oryzae, with an EC50 value of 11.386 μg mL-1, and its curative effect (49.64%) and protection effect (51.74%) on rice bacterial blight disease was equivalent to that of zhongshengmycin (42.90%, 40.80% respectively). Compound 27 could also effectively control gray mold (87.10%, 200 μg mL-1) and rice sheath blight (100%, 200 μg mL-1 82.89%, 100 μg mL-1) in vivo. Preliminary action mechanism study showed that compound 27 mainly acted on the cell membrane and significantly inhibited ergosterol biosynthesis in Colletotrichum musae.

Unsaturated oxime ethers and their use as fungicides

The present invention relates to certain oxime ether compounds, compositions containing these compounds, and methods for controlling fungi by the use of a fungitoxic amount of the compounds or compositions.