175202-25-2 Usage
General Description
N-[4-(trifluoromethyl)benzoyl]-L-methionine methyl ester is a chemical compound that consists of a benzoyl group attached to a methionine molecule, which is further esterified with a methyl group. N-[4-(TRIFLUOROMETHYL)BENZOYL]-L-METHIONINE METHYL ESTER is commonly used in biochemistry and pharmaceutical research as a tool to investigate the role of methionine in protein synthesis and function, as well as in the design and synthesis of potential drug candidates. The presence of the trifluoromethyl group in the benzoyl moiety is of particular interest in medicinal chemistry, as it can confer unique pharmacological properties to the resulting compounds. Additionally, the esterification of the methionine residue can enhance the compound's stability and bioavailability, making it a valuable tool for drug development and research.
Check Digit Verification of cas no
The CAS Registry Mumber 175202-25-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,0 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 175202-25:
(8*1)+(7*7)+(6*5)+(5*2)+(4*0)+(3*2)+(2*2)+(1*5)=112
112 % 10 = 2
So 175202-25-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H16F3NO3S/c1-21-13(20)11(7-8-22-2)18-12(19)9-3-5-10(6-4-9)14(15,16)17/h3-6,11H,7-8H2,1-2H3,(H,18,19)/t11-/m0/s1
175202-25-2Relevant articles and documents
Amide Synthesis by Nickel/Photoredox-Catalyzed Direct Carbamoylation of (Hetero)Aryl Bromides
Alandini, Nurtalya,Buzzetti, Luca,Candish, Lisa,Collins, Karl D.,Favi, Gianfranco,Melchiorre, Paolo,Schulte, Tim
supporting information, p. 5248 - 5253 (2020/03/03)
Herein, we report a one-electron strategy for catalytic amide synthesis that enables the direct carbamoylation of (hetero)aryl bromides. This radical cross-coupling approach, which is based on the combination of nickel and photoredox catalysis, proceeds at ambient temperature and uses readily available dihydropyridines as precursors of carbamoyl radicals. The method's mild reaction conditions make it tolerant of sensitive-functional-group-containing substrates and allow the installation of an amide scaffold within biologically relevant heterocycles. In addition, we installed amide functionalities bearing electron-poor and sterically hindered amine moieties, which would be difficult to prepare with classical dehydrative condensation methods.
