175272-69-2 Usage
Description
(3S,4R)-4-(3-Trifluoromethyl-phenyl)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester is a pyrrolidine derivative ester compound with a tert-butyl group attached to the pyrrolidine ring. It features a trifluoromethyl-phenyl group and a dicarboxylic acid functionality on the pyrrolidine ring, making it a valuable building block for the synthesis of various pharmaceutical compounds. Its stereochemistry, with a 3S configuration and a 4R configuration, is crucial for its biological activity and potential interactions with biological receptors. This versatile and valuable chemical compound has potential applications in drug discovery and development.
Uses
Used in Pharmaceutical Research:
(3S,4R)-4-(3-Trifluoromethyl-phenyl)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester is used as a building block for the synthesis of pharmaceutical compounds due to its unique structure and functional groups.
Used in Drug Design and Development:
(3S,4R)-4-(3-Trifluoromethyl-phenyl)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester is used as a candidate for drug design and development because of its potential therapeutic applications and ability to modulate biological targets.
Used in Organic Chemistry:
(3S,4R)-4-(3-Trifluoromethyl-phenyl)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester is used as a versatile chemical compound in the field of organic chemistry for various synthesis processes and reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 175272-69-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,7 and 2 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 175272-69:
(8*1)+(7*7)+(6*5)+(5*2)+(4*7)+(3*2)+(2*6)+(1*9)=152
152 % 10 = 2
So 175272-69-2 is a valid CAS Registry Number.
175272-69-2Relevant articles and documents
Design and synthesis of ring-constrained boropeptide thrombin inhibitors
Fevig,Abelman,Brittelli,Kettner,Knabb,Weber
, p. 295 - 300 (2007/10/03)
Ring-constrained boropeptide thrombin inhibitors were designed using information from the X-ray crystal structure of 1 (3-phenylpropionyl-Pro-boroLys-OH · HCl) bound to thrombin. The constraints utilized cyclohexane and pyrrolidine rings to preorganize an aromatic ring in an orientation allowing optimum edge-to-face interaction with the tryptophan 215 side chain located in the S3 specificity pocket of thrombin.
