175277-44-8

Basic information

• Product Name: 5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME
• Synonyms: 5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME;5-(Trifluoromethyl)-ALPHA-picolinamide;N'-hydroxy-5-(trifluoromethyl)pyridine-2-carboximidamide;5-(Trifluoromethyl)pyridin-2-carboxamide oxime;5-(Trifluoromethyl)pyridin-2-ylamidoxime;(Z)-N'-hydroxy-5-(trifluoroMethyl)picoliniMidaMide;N-Hydroxy-5-(trifluoroMethyl)picoliniMidaMide;N-hydroxy-5-(trifluoromethyl)-2-Pyridinecarboximidamide
• CAS NO: 175277-44-8
• Molecular Formula: C₇H₆F₃N₃O
• Molecular Weight: 205.14
• EINECS: 604-604-1
• Product Categories: pharmacetical
• Mol File: 175277-44-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 124-126°C
• Boiling Point: 328.112 °C at 760 mmHg
• Flash Point: 152.237 °C
• Appearance: /
• Density: 1.527 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME(175277-44-8)
• EPA Substance Registry System: 5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME(175277-44-8)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 175277-44-8(Hazardous Substances Data)

Usage

General Description

5-(Trifluoromethyl)pyridine-2-carboxamide oxime is a chemical compound that consists of a pyridine ring with a carboxamide group at position 2, along with a trifluoromethyl group attached to the ring. Additionally, it contains an oxime functional group. 5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME has potential applications in various fields such as pharmaceuticals, agrochemicals, and materials science. It may be used in the synthesis of new chemical entities for drug development, as well as in the development of herbicides or pesticides. Furthermore, it can be utilized as a building block for the production of functional materials. Overall, 5-(Trifluoromethyl)pyridine-2-carboxamide oxime has versatile properties that make it valuable in the creation of a wide range of chemical products.

InChI:InChI=1/C7H6F3N3O/c8-7(9,10)4-1-2-5(12-3-4)6(11)13-14/h1-3,14H,(H2,11,13)

Upstream product

• 95727-86-9 2-cyano-5-trifluoro-methylpyridine 

Relevant articles and documents

INHIBITOR COMPOUNDS

The disclosure relates to heterocyclic compounds and methods for their preparation. The disclosure provides compounds that may have beneficial therapeutic activity in the treatment of a disease or condition mediated by excessive or otherwise undesirable Des1 and/or fibrotic activity.

Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, Ar3, A, B and D are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.