175278-08-7

Basic information

• Product Name: 2,3,4-TRIFLUOROBENZENESULFONYL CHLORIDE
• Synonyms: BUTTPARK 44\07-12;2,3,4-TRIFLUOROBENZENE-1-SULFONYL CHLORIDE;2,3,4-TRIFLUOROBENZENESULFONYL CHLORIDE;2,3,4-TRIFLUOROBENZENESULPHONYL CHLORIDE;Benzenesulfonyl chloride, 2,3,4-trifluoro- (9CI);2,3,4-Trifluorobenzenesulphonyl chloride 97%;2,3,4-Trifluorobenzenesulphonylchloride97%;2,3,4-Trifluorobenz
• CAS NO: 175278-08-7
• Molecular Formula: C₆H₂ClF₃O₂S
• Molecular Weight: 230.59
• Product Categories: SULFONYLHALIDE;Aromatic Halides (substituted);Benzenesulfonyl chloride;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Aryl Fluorinated Building Blocks;Building Blocks;C6;Chemical Synthesis;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
• Mol File: 175278-08-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 122-124 °C
• Boiling Point: 234-236 °C(lit.)
• Flash Point: 225 °F
• Appearance: /
• Density: 1.640 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0517mmHg at 25°C
• Refractive Index: n20/D 1.5040(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 2,3,4-TRIFLUOROBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-TRIFLUOROBENZENESULFONYL CHLORIDE(175278-08-7)
• EPA Substance Registry System: 2,3,4-TRIFLUOROBENZENESULFONYL CHLORIDE(175278-08-7)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45-39-37-36
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 175278-08-7(Hazardous Substances Data)

Usage

Description

2,3,4-Trifluorobenzenesulfonyl chloride is an organic compound that serves as a valuable arylating agent in the synthesis of various chemical compounds, particularly in the production of (2,3,4-trifluorophenyl)furan derivatives and other related pyrrole compounds. Its unique structure, featuring trifluorinated benzene and sulfonyl chloride functional groups, makes it a versatile reagent in organic chemistry.

Uses

Used in Pharmaceutical Industry:
2,3,4-Trifluorobenzenesulfonyl chloride is used as an arylating agent for the synthesis of (2,3,4-trifluorophenyl)furan derivatives, which are important intermediates in the development of pharmaceutical compounds. These derivatives exhibit potential biological activities and can be further modified to create novel drugs with improved properties.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2,3,4-Trifluorobenzenesulfonyl chloride is utilized as a key reagent in the preparation of various complex organic molecules, such as 1-(2-bromobenzyl)-2,5-bis(2,3,4-trifluorophenyl)pyrrole and 1-(2-bromobenzyl)-2-(2,3,4-trifluorophenyl)pyrrole. These compounds can be used as building blocks for the development of new materials, dyes, and other specialty chemicals.
Used in Research and Development:
2,3,4-Trifluorobenzenesulfonyl chloride is also employed in research and development laboratories for the exploration of new synthetic routes and the investigation of novel chemical reactions. Its unique reactivity and functional groups make it an attractive candidate for the development of new synthetic methodologies and the discovery of new chemical entities with potential applications in various industries.

InChI:InChI=1/C6H2ClF3O2S/c7-13(11,12)4-2-1-3(8)5(9)6(4)10/h1-2H

Downstream Products

• 283602-38-0 N-cyclopropylmethoxy-2,3,4-trifluoro-benzenesulfonamide 

Relevant articles and documents

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