175416-53-2

Basic information

• Product Name: (5R)-3-tert-butyl-5-phenyl-3,4,5,6-tetrahydro-1,4-oxazin-2-one
• Synonyms: (5R)-3-tert-butyl-5-phenyl-3,4,5,6-tetrahydro-1,4-oxazin-2-one
• CAS NO: 175416-53-2
• Molecular Weight: 233.31
• Mol File: 175416-53-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5R)-3-tert-butyl-5-phenyl-3,4,5,6-tetrahydro-1,4-oxazin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-3-tert-butyl-5-phenyl-3,4,5,6-tetrahydro-1,4-oxazin-2-one(175416-53-2)
• EPA Substance Registry System: (5R)-3-tert-butyl-5-phenyl-3,4,5,6-tetrahydro-1,4-oxazin-2-one(175416-53-2)

Safety Data

• Hazardous Substances Data: 175416-53-2(Hazardous Substances Data)

Upstream product

• 175226-69-4 (5R)-3-tert-butyl-5-phenyl-5,6-dihydro-2H-1,4-oxazin-2-one 

Downstream Products

• 1009606-13-6 (3S,5R)-4-benzyl-3-(tert-butyl)-5-phenylmorpholin-2-one 
• 139163-43-2 (S)-2-amino-3,3-dimethylbutanoic acid hydrochloride 

Relevant articles and documents

An efficient entry to optically active anti- and syn-β-amino-α- trifluoromethyl alcohols

The reaction of chiral 5,6-dihydro-2H-1,4-oxazin-2-ones with TMSCF 3 in the presence of a suitable activator leads to trifluoromethyl lactols, which can be selectively reduced to anti-β-amino-α- trifluoromethyl alcohols. The corresponding syn d