175601-94-2 Usage
General Description
2,3-dihydro-1H-Indole-3-acetamide is an organic compound belonging to the indole class of chemicals. It is a derivative of indole and has a molecular structure consisting of a 2,3-dihydroindole ring with an acetamide group attached at the 3-position. 2,3-dihydro-1H-Indole-3-acetaMide has biological significance and is commonly used as a intermediate in the synthesis of various pharmaceuticals and biologically active compounds. It has been studied for its potential pharmacological properties, including its activity as a central nervous system stimulant and its potential as a drug candidate for neurological disorders. Additionally, its chemical structure and properties make it highly versatile for use in organic synthesis and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 175601-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,6,0 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 175601-94:
(8*1)+(7*7)+(6*5)+(5*6)+(4*0)+(3*1)+(2*9)+(1*4)=142
142 % 10 = 2
So 175601-94-2 is a valid CAS Registry Number.
175601-94-2Relevant articles and documents
[11C]Enzastaurin, the first design and radiosynthesis of a new potential PET agent for imaging of protein kinase C
Wang, Min,Xu, Lu,Gao, Mingzhang,Miller, Kathy D.,Sledge, George W.,Zheng, Qi-Huang
experimental part, p. 1649 - 1653 (2011/05/11)
Enzastaurin (LY317615) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 value of ~6 nM. [11C] Enzastaurin (3-(1-[11C]methyl-1H-indol-3-yl)-4-[1-[1-(2- pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione), a new potential PET agent for imaging of PKC, was first designed and synthesized in 20-25% decay corrected radiochemical yield and 370-555 GBq/μmol specific activity at end of bombardment (EOB). The synthetic strategy was to prepare a carbon-11-labeled maleic anhydride intermediate followed by the conversion to maleimide.