17598-94-6Relevant articles and documents
Biocatalytic esterification in supercritical carbon dioxide by using a lipid-coated lipase
Mori, Toshiaki,Kobayashi, Atsushi,Okahata, Yoshio
, p. 921 - 922 (1998)
A lipid-coated lipase is soluble and acts as a more efficient catalyst for triglyceride syntheses in supercritical carbon dioxide (scCO2) than in conventional organic solvents, and the reactivity can be controlled reversibly by changing pressure and temperature in scCO2.
4-O-Acetyl-3-O-tert-butyldimethylsilyl-l-rhamnal: a building block in the stereoselective synthesis of 2-deoxy-α-l-rhamnopyranosides
Wandzik, Ilona,Bieg, Tadeusz
, p. 2702 - 2707 (2006)
The stereoselective synthesis of 2-deoxy-α-l-glycosides by addition of various acceptors to 4-O-acetyl-3-O-tert-butyldimethylsilyl-l-rhamnal promoted by triphenylphosphine-hydrogen bromide is developed.
Selective synthesis of glyceryl monolaurate intensified by boric acid based deep eutectic solvent
Chen, Lifang,Cheng, Hongye,Qi, Zhiwen,Shen, Zilong
, (2021/06/21)
Glyceryl monolaurate (GML), as one of widely used industrial chemicals, can be synthesized via Fischer esterification of lauric acid (LA) and glycerol (GL). In this work, we screened boric acid-based deep eutectic solvent (DES) formed from tetrapropylammonium bromide (TPAB) and boric acid to intensify the selective Fischer esterification through conductor-like screening model for realistic solvents (COSMO-RS) theory. The solid liquid equilibrium (SLE) phase behavior, hydrogen bond formation process, and thermal stability of the DES were characterized by differential scanning calorimetry (DSC), Fourier transform infrared spectrometry (FT-IR), and thermogravimetric analyzer (TGA). The results verified that equimolar TPAB and boric acid formed DES [TPAB:B(OH)3] with the lowest freezing point and very good thermal stability could efficiently intensify the Fischer esterification of GL and LA to GML. The hydrogen bond accepter TPAB of the DES made the esterification system homogeneous, which promoted the selective esterification process. In addition, the hydrogen bond donor B(OH)3 of the [TPAB:B(OH)3] combined with diol unit of GL to cyclic boric esters and led to a special selective space effect, which also improved the selectivity to GML. Thus, the esterification intensified of GL and LA by 20 wt% DES achieved GML selectivity of 85.7 % and yield of 76.4 % under the optimal reaction conditions. The esterification kinetics suggested the reaction followed pseudo-second-order model and the reaction activation energy was 33.98 kJ mol?1, similar to and/or lower than those reported works. Furthermore, DES and unreacted glycerol were readily recovered and reused through temperature controlled gravity-based separation due to the ability of homogeneity under reaction conditions and splitting phase behavior during the DES recovery. The results can expand the boric acid-based DESs for other potential intensification applications.
1,2-Diacrylglycerol and wherein the intermediate preparation method
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Paragraph 0138-0139, (2017/01/23)
The invention discloses a preparation method for diacylglycero and an intermediate thereof. The preparation method for diacylglycero comprises the following steps: in an ether solvent and/or an alcohol solvent, in the present of an alkali, performing hydrolysis reaction on a compound shown as a formula 5, so as to obtain diacylglycero which is 1 shown in a formula 1. R in the formula 5 and 5 is C14-C18 saturated or unsaturated aliphatic acyl. The preparation method is cheap in raw materials, mild in reaction conditions, safe in operation, simple in postprocessing operation, high in reaction conversion rate, high in yield and suitable for large-scale production.