176208-39-2

Basic information

• Product Name: dimethyl N-<4-<2-(2-amino-4(3H)-oxothieno<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate
• Synonyms: dimethyl N-<4-<2-(2-amino-4(3H)-oxothieno<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate
• CAS NO: 176208-39-2
• Molecular Weight: 472.522
• Mol File: 176208-39-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl N-<4-<2-(2-amino-4(3H)-oxothieno<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl N-<4-<2-(2-amino-4(3H)-oxothieno<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate(176208-39-2)
• EPA Substance Registry System: dimethyl N-<4-<2-(2-amino-4(3H)-oxothieno<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate(176208-39-2)

Safety Data

• Hazardous Substances Data: 176208-39-2(Hazardous Substances Data)

Upstream product

• 23150-65-4 L-glutamic dimethyl ester hydrochloride 
• 149010-58-2 4-<2-(2-amino-4(3H)-oxothieno<2,3-d>pyrimidin-5-yl)ethyl>benzoic acid 
• 149010-52-6 1-chloro-4-(4-carbomethoxyphenyl)-2-butanone 
• 176208-31-4 4-<2-amino-4(3H)-oxopyrimidin-6-yl>thio-4-(4-carbomethoxyphenyl)-2-butanone 

Relevant articles and documents

Synthesis of thieno[2,3-d]pyrimidine analogues of the potent antitumor agent N-{4-[2-(2-amino-4(3H)-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-YL)ethyl-benzoyl}-L- glutamic acid (LY231514)

Several thieno[2,3-d]pyrimidine analogues of the potent antitumor agent N-{4-[2-(2-amino-4(3H)-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-benzoyl}-L- glutamic acid (LY231514, 7) have been prepared by two different strategies. The first involved S-alkylati