17624-08-7

Basic information

• Product Name: 6-CHLOROPYRIDINE-3-SULFONIC ACID
• Synonyms: 6-CHLOROPYRIDINE-3-SULFONIC ACID;IFLAB-BB F2124-0034;2-Chloro-5-pyridinecarboxylicacid;6-CHLORO-3-PYRIDINESULFONIC ACID
• CAS NO: 17624-08-7
• Molecular Formula: C5H4ClNO3S
• Molecular Weight: 193.61
• Product Categories: Pyridines
• Mol File: 17624-08-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 242-243℃
• Appearance: /
• Density: 1.649
• Refractive Index: 1.592
• Storage Temp.: 2-8°C
• PKA: -1.45±0.50(Predicted)
• CAS DataBase Reference: 6-CHLOROPYRIDINE-3-SULFONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLOROPYRIDINE-3-SULFONIC ACID(17624-08-7)
• EPA Substance Registry System: 6-CHLOROPYRIDINE-3-SULFONIC ACID(17624-08-7)

Safety Data

• Hazardous Substances Data: 17624-08-7(Hazardous Substances Data)

Usage

General Description

6-Chloropyridine-3-sulfonic acid is a chemical compound with the molecular formula C5H4ClNO3S. It is a sulfonic acid derivative of pyridine, and its chemical structure consists of a pyridine ring substituted with a chlorine atom and a sulfonic acid group at the 3-position. 6-CHLOROPYRIDINE-3-SULFONIC ACID is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals. It is also used as a reagent in organic synthesis and as a catalyst in chemical reactions. 6-Chloropyridine-3-sulfonic acid is a water-soluble compound that is typically handled and stored as a solid. It is important to handle this compound with care and in accordance with proper safety protocols, as it can be hazardous if not handled properly.

InChI:InChI=1/C5H4ClNO3S/c6-5-2-1-4(3-7-5)11(8,9)10/h1-3H,(H,8,9,10)

Upstream product

• 6684-39-5 2-chloropyridine-5-sulfonyl chloride 
• 6684-46-4 6-hydroxy-pyridine-3-sulfonic acid 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 

Downstream Products

• 38030-00-1 2-(4-Methyl-1-piperazinyl)-pyridin-5-sulfonsaeure 

Relevant articles and documents

Preparation method of aromatic sulfonic acid compound

The invention discloses a preparation method of an aromatic sulfonic acid compound, and aims to provide the preparation method of the aromatic sulfonic acid compound, wherein the method is simple in process, low in equipment requirements, high in capacity, wide in raw material sources and small in environmental influence. The method is characterized by comprising the steps: with a starting material aromatic amine compound, dissolving in an acid, carrying out a diazotization reaction with sodium nitrite to prepare a diazocompound; carrying out a reaction of a catalyst cuprous salt with a thionyl chloride aqueous solution, and carrying out a sulfonylation reaction with the prepared diazocompound to obtain an aromatic sulfonyl chloride compound or an aromatic sulfonyl chloride hydrochloride compound, next hydrolyzing to obtain a crude product aromatic sulfonic acid compound, finally purifying through a beating way by an acidic solvent and an alcohol solution, and thus obtaining the high-purity aromatic sulfonic acid compound. The method is friendly to environment, has certain cost advantages, avoids use of more expensive aromatic thiol compounds as starting materials, and is beneficial for industrial production.