176245-06-0Relevant articles and documents
1-N-Iminosugars: Potent and selective inhibitors of β-glycosidases
Ichikawa, Yoshitaka,Igarashi, Yasuhiro,Ichikawa, Mie,Suhara, Yoshitomo
, p. 3007 - 3018 (2007/10/03)
A series of 1-N-iminosugars were synthesized to supply the need for glycosidase inhibitors that are both highly potent and selective for β- glycosidases. Designed on the basis of the transition-state model of the β- glucosidase reaction, these iminosugar