17663-34-2

Basic information

• Product Name: L-Leucine, 4-nitrophenyl ester
• CAS NO: 17663-34-2
• Molecular Formula: C12H16N2O4
• Molecular Weight: 252.27
• Mol File: 17663-34-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Leucine, 4-nitrophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, 4-nitrophenyl ester(17663-34-2)
• EPA Substance Registry System: L-Leucine, 4-nitrophenyl ester(17663-34-2)

Safety Data

• Hazardous Substances Data: 17663-34-2(Hazardous Substances Data)

Upstream product

• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 100-02-7 4-nitro-phenol 
• 1738-87-0 Z-Leu-ONp 
• 3350-19-4 (tert-butoxycarbonyl)-L-leucine p-nitrobenzylester 

Downstream Products

• 100-02-7 4-nitro-phenol 
• 61-90-5 L-leucine 
• 328-38-1 (R)-leucine 

Relevant articles and documents

Kinetic study on conformational effect in hydrolysis of p-nitroanilides catalyzed by α-chymotrypsin

Effects of medium viscosity on kinetics for the hydrolysis of p-nitroanilides of certain amino acid derivatives catalyzed by α-chymotrypsin have been investigated. Observed data indicate that the overall rate constant, kcat, is hardly affected by the medium viscosity in all the substrates employed and equals the rate constant at the acylation step, k2, in the measured range of viscosity. By comparison with the data on p-nitrophenyl ester substrates reported previously, it is concluded that the formation of the tetrahedral intermediate in the course of the acylation of the enzyme is influenced by conformational change of the enzyme, whereas the breakdown of the intermediate is almost free from conformational effects.