1770812-37-7 Usage
Description
(S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)thiophene-2-carboxaMide is a complex organic compound with a specific molecular structure. It is characterized by the presence of a thiophene ring, a carboxyamide group, and various other functional groups that contribute to its chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
(S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)thiophene-2-carboxaMide is used as an impurity in the production of Rivaroxaban (R538000), a novel antithrombotic agent. Rivaroxaban is a highly potent and selective, direct FXa inhibitor, which plays a crucial role in the prevention and treatment of various thrombotic disorders.
As an impurity in the synthesis of Rivaroxaban, (S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)thiophene-2-carboxaMide may have implications for the overall efficacy, safety, and quality control of the final drug product. Therefore, its presence and concentration need to be carefully monitored and controlled during the manufacturing process to ensure the desired therapeutic outcomes and minimize potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1770812-37-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,7,7,0,8,1 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1770812-37:
(9*1)+(8*7)+(7*7)+(6*0)+(5*8)+(4*1)+(3*2)+(2*3)+(1*7)=177
177 % 10 = 7
So 1770812-37-7 is a valid CAS Registry Number.
1770812-37-7Relevant articles and documents
A related substance [...] F, G synthetic method
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Paragraph 0085-0089; 0092; 0095, (2018/03/01)
The invention provides synthetic methods of related substances F and G of rivaroxaban. With the adoption of the synthetic methods of the related substances F and G of the rivaroxaban, the yield is high, and industrial production and technology transformation are realized easily.
An Improved Synthesis of Rivaroxaban
Tian, Shaixiao,Tang, Bo,Zhang, Minzhong,Gao, Qingjiao,Chen, Bo,Zhang, Qinghua,Xu, Guangyu
, p. 169 - 177 (2017/04/26)
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