17721-00-5

Basic information

• Product Name: 5-Thiazolamine
• Synonyms: 5-Thiazolamine;Thiazol-5-amine;5-AMINOTHIAZOLE;5-THIAZOLAMINE 99%;5-Amino-1,3-thiazole;1,3-Thiazol-5-amine;5-ThiazolaMine hydrochloride
• CAS NO: 17721-00-5
• Molecular Formula: C₃H₄N₂S
• Molecular Weight: 100.14
• Product Categories: Thiazole;API;Thiazoles;Building Blocks
• Mol File: 17721-00-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 239.313 °C at 760 mmHg
• Flash Point: 98.533 °C
• Appearance: /
• Density: 1.345 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 4.01±0.10(Predicted)
• CAS DataBase Reference: 5-Thiazolamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolamine(17721-00-5)
• EPA Substance Registry System: 5-Thiazolamine(17721-00-5)

Safety Data

• Hazardous Substances Data: 17721-00-5(Hazardous Substances Data)

Usage

General Description

5-Thiazolamine is a chemical compound that contains a thiazole ring and an amine group. It is a heterocyclic organic compound that is commonly used in the synthesis of pharmaceuticals and agrochemicals. It possesses antibacterial and antifungal properties, making it useful for a variety of applications in the medical and agricultural industries. Additionally, 5-Thiazolamine has been found to exhibit antioxidant and anti-inflammatory properties, further expanding its potential uses in the field of medicinal chemistry. Its versatile nature and biological activities make it an important and valuable chemical compound in various scientific and industrial fields.

InChI:InChI=1/C3H4N2S.ClH/c4-3-1-5-2-6-3;/h1-2H,4H2;1H

Upstream product

• 99972-05-1 N-thiazol-5-yl-phthalimide 
• 5018-27-9 N-formylamino-acetonitrile 
• 14527-41-4 thiazole-5-carboxylic acid 

Downstream Products

• 408507-23-3 N-(thiazol-5-yl)acetamide 
• 129624-30-2 5-phenylacetylaminothiazole 
• 2007-19-4 1-nitroso-2-naphthol-3,6-disulfonic acid 
• 1415677-84-7 methyl (2Z)-4-{(1R,3aS,5S,11R,14aS)-3a,4,5,7-tetrahydro-8-methoxy-3,3,11-trimethyl-11-(4-methylpent-3-en-1-yl)-13-[(2E)-3-methyl-4-(thiazol-5-ylamino)but-2-en-1-yl]-7,15-dioxo-3H,11H-1,5-methanofuro[3,4-g]pyrano[3,2-b]xanthen-1-yl}-2-methylbut-2-enoate 
• 1227044-24-7 C₁₈H₁₈N₄S 
• 111797-05-8 N-acetyl-4-[bis-(2-chloro-ethyl)-amino]-phenylalanine thiazol-5-ylamide 

Relevant articles and documents

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Mechanism of azo coupling reactions. Part 34. Reactivity of five-membered ring heteroaromatic diazonium ions

The azo coupling reactions of six five-membered heteroaromatic diazonium ions with 2-naphthol-3,6-disulfonic acid are investigated kinetically at various pH values.The dependence of the measured rate constants on the acidity of the aqueous reaction system is evaluated.It can be shown that the 2-naphtholate-3,6-disulfonate trianion reacts 4E8 - 8E8 times faster than the 2-naphthol-3,6-disulfonate dianion.The rate constants of the six diazonium ions vary by more than four orders of magnitude.The logarithms of the rate constants of all comparable diazonium ions correlate linearly with 1H-nmr chemical shifts of the respective unsubstituted heteroaromatic parent compounds.An analogous correlation was found for azo couplings with substituted benzenediazonium ions.Diazotization of heteroaromatic amines does not go to completion, rather to an equilibrium.It is shown therefore that in acidic coupling systems the azo compound is only the kinetically controlled product.The thermodynamic products are 1-nitroso-2-naphthol-3,6-disulfonic acid and the heteroaromatic amine.