177212-63-4Relevant articles and documents
Synthesis of the interferon-α inducer imiquimod by thermal electrocyclic reactions of 1- and 2-azahexatriene systems
Yoshioka, Haruyuki,Matsuya, Yuhji,Choshi, Tominari,Sugino, Eiichi,Hibino, Satoshi
, p. 709 - 714 (2007/10/03)
The interferon-α inducer imiquimod (1), possessing an imidazo[4,5- c]quinoline ring, has been newly synthesized by two routes on thermal electrocyclic reactions of 1- and 2-azahexatriene systems involving the imidazole 4,5-bond.