1773-49-5

Basic information

• Product Name: 4-Methoxybenzaldehyde 2,4-dinitrophenyl hydrazone
• Synonyms: 4-Methoxybenzaldehyde 2,4-dinitrophenyl hydrazone
• CAS NO: 1773-49-5
• Molecular Formula: C₁₄H₁₂N₄O₅
• Molecular Weight: 316.2689
• Mol File: 1773-49-5.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 488.2°Cat760mmHg
• Flash Point: 249.1°C
• Appearance: /
• Density: 1.39g/cm³
• Vapor Pressure: 1.11E-09mmHg at 25°C
• Refractive Index: 1.629
• CAS DataBase Reference: 4-Methoxybenzaldehyde 2,4-dinitrophenyl hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxybenzaldehyde 2,4-dinitrophenyl hydrazone(1773-49-5)
• EPA Substance Registry System: 4-Methoxybenzaldehyde 2,4-dinitrophenyl hydrazone(1773-49-5)

Safety Data

• Hazardous Substances Data: 1773-49-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H12N4O5/c1-23-12-5-2-10(3-6-12)9-15-16-13-7-4-11(17(19)20)8-14(13)18(21)22/h2-9,16H,1H3

Upstream product

• 85468-48-0 N-(p-methoxybenzylidene)aminophthalimide 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 123-11-5 4-methoxy-benzaldehyde 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 2393-23-9 4-methoxy-benzylamine 
• 105-13-5 4-Methoxybenzyl alcohol 
• 3717-21-3 p-methoxyl benzaldoxime 
• 104-46-1 anethole 
• 33472-11-6 [hydroxy-(4-methoxy-phenyl)-methyl]-phosphonic acid diisopropyl ester 
• 637-69-4 4-Methoxystyrene 
• 64445-49-4 2.4-Dinitro-benzol-diazonium-⁽¹⁾-sulfat 

Downstream Products

• 74519-25-8 (2,4-Dinitro-phenyl)-[(4-methoxy-phenyl)-(triphenyl-λ⁵-phosphanylidene)-methyl]-diazene 
• 79348-70-2 C₁₄H₁₁ClN₄O₅ 
• 123-11-5 4-methoxy-benzaldehyde 
• 74527-20-1 C₁₄H₁₁BrN₄O₅ 

Relevant articles and documents

2,4-Dinitrophenyl hydrazone derivatives as potent alpha amylase inhibitors

In our current study thirteen new 2,4-dinitrophenyl hydrazone derivatives 1-13 have been evaluated for alpha amylase activity. The molecular docking results indicate that compounds potentially bind in the catalytic site of the enzyme with excellent result. Molecular Operating Environment (MOE) software was used for docking study. 2,4-Dinitrophenyl hydrazone 1-13 have been obtained under reflux conditions by reacting dinitrophenyl hydrazine in methanol with different aromatic as well as aliphatic aldehydes in the presence of acetic acid act as a catalyst. The current results have shown that compounds 5 (IC50 =12.16μg/mL), 6 (IC50 =15.03μg/mL), and 12 (IC50 =16.42 μg/mL) have been found to be the more potent alpha amylase inhibitors as compared to the standard acarbose (IC50 = 42.47μg/mL). These compounds may provide better leads for alpha amylase inhibitor and further assessment of these compounds can be of great help in the discovery of new antidiabetic drugs.

Synthesis, structural characterization, and antioxidant activities of 2,4-dinitrophenyl-hydrazone derivatives

Thirty-two derivatives of 2,4-dinitro phenylhydrazone 1-32 were synthesized by one step reaction and characterized by spectroscopic techniques such as EI-MS and 1H-NMR. Compounds 1-32 were screened for their in vitro antioxidant activities. DPPH radical s

Synthesis, characterization and biological evaluation of substituted novel pyrazolone and pyrazole derivatives

In the present investigation, series of 2-(4-methoxybenzyl) substituted-3-methyl- 1,2-dihydropyrazol-5-one and 2-(4-methoxybenzyl)-substituted-3,5-dimethyl-2,5-dihydro- 1H-pyrazole have been synthesized. All synthesized compounds were characterized and te