17730-93-7 Usage
Description
[2-(4-nitrophenyl)-2-oxoethyl](triphenyl)phosphonium, an organophosphorus compound with the molecular formula C27H22NO3P, features a phosphonium cation with both a 4-nitrophenyl group and a triphenylphosphine group. [2-(4-nitrophenyl)-2-oxoethyl](triphenyl)phosphonium is recognized for its role in organic chemistry, particularly in synthetic processes and Wittig reactions for alkene preparation from aldehydes or ketones. Due to its toxicity, it is essential to handle this compound with care and only under controlled laboratory conditions.
Uses
Used in Organic Chemistry:
[2-(4-nitrophenyl)-2-oxoethyl](triphenyl)phosphonium is used as a reactant in various synthetic processes for its ability to participate in Wittig reactions, which are crucial for the preparation of alkenes from aldehydes or ketones. This application is significant in the synthesis of complex organic molecules and pharmaceutical compounds.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, [2-(4-nitrophenyl)-2-oxoethyl](triphenyl)phosphonium is used as a reagent for the synthesis of various drugs. Its role in Wittig reactions allows for the creation of specific alkenes that are vital building blocks in the development of pharmaceutical compounds.
Used in Research and Development:
[2-(4-nitrophenyl)-2-oxoethyl](triphenyl)phosphonium is also utilized in research and development settings, where it aids in the exploration of new synthetic pathways and the development of novel chemical reactions. Its application in this context is essential for advancing the field of organic chemistry and discovering new methods for creating complex molecules.
Used in Material Science:
In material science, [2-(4-nitrophenyl)-2-oxoethyl](triphenyl)phosphonium may be employed as a component in the synthesis of advanced materials, such as polymers and composites, that require specific structural features. Its ability to participate in Wittig reactions can be leveraged to create unique molecular structures with tailored properties.
Overall, [2-(4-nitrophenyl)-2-oxoethyl](triphenyl)phosphonium is a versatile reagent in the fields of organic chemistry, pharmaceutical synthesis, research and development, and material science, with applications in various chemical reactions and the creation of complex molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 17730-93-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,7,3 and 0 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 17730-93:
(7*1)+(6*7)+(5*7)+(4*3)+(3*0)+(2*9)+(1*3)=117
117 % 10 = 7
So 17730-93-7 is a valid CAS Registry Number.
17730-93-7Relevant articles and documents
Rh(iii)-catalyzed diastereoselective cascade annulation of enone-tethered cyclohexadienonesviaC(sp2)-H bond activation
Chegondi, Rambabu,Jadhav, Sandip B.,Maurya, Sundaram,Navaneetha, N.
supporting information, p. 13598 - 13601 (2021/12/23)
Herein, we report highly diastereoselective arylative cyclization of enone-tethered cyclohexadienonesviaRh(iii)-catalyzed C-H activation ofN-methoxybenzamides. This reaction proceeds through the formation of a five-membered rhodacycle followed by bis-Michael cascade annulation to access functionalized bicyclic scaffolds with four contiguous stereocenters with a broad substrate scope. These products have excellent functional handles, allowing further synthetic transformation to increase the structural complexity. Furthermore, mechanistic studies of arylative cyclization and a gram-scale experiment are also presented.
A Ba/Pd Catalytic System Enables Dehydrative Cross-Coupling and Excellent E-Selective Wittig Reactions
Xie, Peizhong,Fu, Weishan,Cai, Xinying,Sun, Zuolian,Wu, Ying,Li, Shuangshuang,Gao, Cuiqing,Yang, Xiaobo,Loh, Teck-Peng
supporting information, p. 7055 - 7059 (2019/09/12)
A Ba/Pd cooperative catalysis system was developed to enable the dehydrative cross-coupling of allylic alcohols with P-ylides to occur directly and promote a subsequent Wittig reaction in one pot. A variety of multisubstituted 1,4-dienes were isolated in good to excellent yields with broad P-ylides (stabilized by both ester and ketone carbonyl groups) and aldehyde (aliphatic and aromatic) substrates with excellent E selectivity.
Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a] pyrimidine derivatives
Massari, Serena,Desantis, Jenny,Nannetti, Giulio,Sabatini, Stefano,Tortorella, Sara,Goracci, Laura,Cecchetti, Violetta,Loregian, Arianna,Tabarrini, Oriana
supporting information, p. 7944 - 7955 (2017/10/06)
Two facile and efficient one-step procedures for the regioselective synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidines have been developed, via reactions of 3,5-diamino-1,2,4-triazole with variously substituted 1-a
