177489-90-6

Basic information

• Product Name: (3-AMINO-1-METHYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (3-AMINO-1-METHYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER;3-BOC-AMINO-BUTYLAMINE;Carbamic acid, (3-amino-1-methylpropyl)-, 1,1-dimethylethyl ester (9CI);(3-Amino-1-methylpropyl)carbamic acid 1,1-dimethylethyl ester;3-Boc-amino-1-butylamine
• CAS NO: 177489-90-6
• Molecular Formula: C9H20N2O2
• Molecular Weight: 188.27
• Product Categories: N-BOC
• Mol File: 177489-90-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: (3-AMINO-1-METHYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-AMINO-1-METHYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER(177489-90-6)
• EPA Substance Registry System: (3-AMINO-1-METHYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER(177489-90-6)

Safety Data

• Hazardous Substances Data: 177489-90-6(Hazardous Substances Data)

Usage

General Description

(3-Amino-1-methyl-propyl)-carbamic acid tert-butyl ester is a chemical compound that is commonly used as a reagent in organic synthesis and as an intermediate in the production of pharmaceuticals. It is a carbamate ester, which is a type of compound that contains a carbamate functional group. This chemical is also known for its potential applications as an insecticide and herbicide. It should be handled and used with caution, as it may pose risks to human health and the environment if not properly managed.

Upstream product

• 177489-74-6 1-Azido-3-isocyanato-butane 
• 126301-16-4 (2S)-2-[(tert-butoxycarbonyl)amino]propyl methanesulfonate 
• 79069-13-9 (S)-2-t-butoxycarbonylaminopropan-1-ol 
• 79069-13-9 (R)-2-tertbutoxycarbonylamino-1-propanol 
• 126301-16-4 (2R)-2-[(tert-butoxycarbonyl)amino]propyl methanesulfonate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 170367-68-7 (2-cyano-1(R)-methylethyl)carbamic acid, 1,1-dimethylethyl ester 
• 172695-22-6 (2-cyano-1(S)-methylethyl)carbamic acid, 1,1-dimethylethyl ester 

Downstream Products

• 1327336-78-6 C₂₉H₃₇BrN₄O₄ 

Relevant articles and documents

TRIAZACYCLODODECANSULFONAMIDE ("TCD")-BASED PROTEIN SECRETION INHIBITORS

Provided herein are triazacyclododecansulfonamide ("TCD")-based protein secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same. For example, provided herein are compounds of Formula (I) and pharmaceutically acceptable salts and compositions including the same. The compounds disclosed herein may be used, for example, in the treatment of diseases including inflammation and/or cancer.

Synthesis of novel optical isomers of α-methylpolyamines

Earlier unknown (R)- and (S)-α-methylspermidine, (R)- and (S)-α-methylspermine, (R,R)-, (S,S)-, and (R,S)-α,ω-dimethylspermine were synthesized in gram scale from readily available (R)- and (S)-2-aminopropanols in high overall yields.

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

The present invention is to provide a novel compound (I), having the anti-virus activity, particularly the HIV integrase inhibitory activity, and a drug containing the same, particularly an anti-HIV drug, as well as a process and an intermediate thereof. Compound (I) wherein Z1 is NR4; R1 is hydrogen or lower alkyl; X is a single bond, a hetero atom group selected from O, S, SO, SO2 and NH, or lower alkylene or lower alkenylene in which the hetero atom group may intervene; R2 is optionally substituted aryl; R3 is hydrogen, a halogen, hydroxy, optionally substituted lower alkyl etc; and R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.